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Synergy of the antibiotic colistin with echinocandin antifungals in Candida species.
Zeidler U, Bougnoux ME, Lupan A, Helynck O, Doyen A, Garcia Z, Sertour N, Clavaud C, Munier-Lehmann H, Saveanu C, d'Enfert C. Zeidler U, et al. Among authors: helynck o. J Antimicrob Chemother. 2013 Jun;68(6):1285-96. doi: 10.1093/jac/dks538. Epub 2013 Feb 1. J Antimicrob Chemother. 2013. PMID: 23378416 Free article.
High content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discovery.
Aulner N, Danckaert A, Rouault-Hardoin E, Desrivot J, Helynck O, Commere PH, Munier-Lehmann H, Späth GF, Shorte SL, Milon G, Prina E. Aulner N, et al. Among authors: helynck o. PLoS Negl Trop Dis. 2013 Apr 4;7(4):e2154. doi: 10.1371/journal.pntd.0002154. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23593521 Free PMC article.
Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity.
Lucas-Hourani M, Dauzonne D, Jorda P, Cousin G, Lupan A, Helynck O, Caignard G, Janvier G, André-Leroux G, Khiar S, Escriou N, Desprès P, Jacob Y, Munier-Lehmann H, Tangy F, Vidalain PO. Lucas-Hourani M, et al. Among authors: helynck o. PLoS Pathog. 2013;9(10):e1003678. doi: 10.1371/journal.ppat.1003678. Epub 2013 Oct 3. PLoS Pathog. 2013. PMID: 24098125 Free PMC article.
Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).
Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YL. Lucas-Hourani M, et al. Among authors: helynck o. J Med Chem. 2015 Jul 23;58(14):5579-98. doi: 10.1021/acs.jmedchem.5b00606. Epub 2015 Jun 30. J Med Chem. 2015. PMID: 26079043 Free PMC article.
21 results