Helmes M - Search Results

1

EGFR/IGF1R Signaling Modulates Relaxation in Hypertrophic Cardiomyopathy.

Algül S, Schuldt M, Manders E, Jansen V, Schlossarek S, de Goeij-de Haas R, Henneman AA, Piersma SR, Jimenez CR, Michels M, Carrier L, Helmes M, van der Velden J, Kuster DWD. Algül S, et al. Among authors: helmes m. Circ Res. 2023 Aug 18;133(5):387-399. doi: 10.1161/CIRCRESAHA.122.322133. Epub 2023 Jul 21. Circ Res. 2023. PMID: 37477020 Free article.

2

Selective phosphorylation of PKA targets after β-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model.

Najafi A, Sequeira V, Helmes M, Bollen IA, Goebel M, Regan JA, Carrier L, Kuster DW, Van Der Velden J. Najafi A, et al. Among authors: helmes m. Cardiovasc Res. 2016 May 15;110(2):200-14. doi: 10.1093/cvr/cvw026. Epub 2016 Jan 29. Cardiovasc Res. 2016. PMID: 26825555

3

Real-Time Measurements of Calcium and Contractility Parameters in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Dinani R, Manders E, Helmes M, Wang L, Knollmann B, Kuster DWD, van der Velden J. Dinani R, et al. Among authors: helmes m. J Vis Exp. 2023 May 26;(195). doi: 10.3791/65326. J Vis Exp. 2023. PMID: 37306462

4

End-diastolic force pre-activates cardiomyocytes and determines contractile force: role of titin and calcium.

Najafi A, van de Locht M, Schuldt M, Schönleitner P, van Willigenburg M, Bollen I, Goebel M, Ottenheijm CAC, van der Velden J, Helmes M, Kuster DWD. Najafi A, et al. Among authors: helmes m. J Physiol. 2019 Sep;597(17):4521-4531. doi: 10.1113/JP277985. Epub 2019 Jul 30. J Physiol. 2019. PMID: 31314138 Free PMC article.

5

Cardiac Microvascular Endothelial Enhancement of Cardiomyocyte Function Is Impaired by Inflammation and Restored by Empagliflozin.

Juni RP, Kuster DWD, Goebel M, Helmes M, Musters RJP, van der Velden J, Koolwijk P, Paulus WJ, van Hinsbergh VWM. Juni RP, et al. Among authors: helmes m. JACC Basic Transl Sci. 2019 Sep 4;4(5):575-591. doi: 10.1016/j.jacbts.2019.04.003. eCollection 2019 Sep. JACC Basic Transl Sci. 2019. PMID: 31768475 Free PMC article.

6

Large-Scale Contractility Measurements Reveal Large Atrioventricular and Subtle Interventricular Differences in Cultured Unloaded Rat Cardiomyocytes.

Nollet EE, Manders EM, Goebel M, Jansen V, Brockmann C, Osinga J, van der Velden J, Helmes M, Kuster DWD. Nollet EE, et al. Among authors: helmes m. Front Physiol. 2020 Jul 21;11:815. doi: 10.3389/fphys.2020.00815. eCollection 2020. Front Physiol. 2020. PMID: 32848817 Free PMC article.

7

Automatic detection of adult cardiomyocyte for high throughput measurements of calcium and contractility.

Cao L, Manders E, Helmes M. Cao L, et al. Among authors: helmes m. PLoS One. 2021 Sep 1;16(9):e0256713. doi: 10.1371/journal.pone.0256713. eCollection 2021. PLoS One. 2021. PMID: 34469476 Free PMC article.

8

High Fibroblast Growth Factor 23 concentrations in experimental renal failure impair calcium handling in cardiomyocytes.

Verkaik M, Oranje M, Abdurrachim D, Goebel M, Gam Z, Prompers JJ, Helmes M, Ter Wee PM, van der Velden J, Kuster DW, Vervloet MG, Eringa EC; NIGRAM consortium. Verkaik M, et al. Among authors: helmes m. Physiol Rep. 2018 Apr;6(7):e13591. doi: 10.14814/phy2.13591. Physiol Rep. 2018. PMID: 29611320 Free PMC article.

9

Synergistic role of ADP and Ca(2+) in diastolic myocardial stiffness.

Sequeira V, Najafi A, McConnell M, Fowler ED, Bollen IA, Wüst RC, dos Remedios C, Helmes M, White E, Stienen GJ, Tardiff J, Kuster DW, van der Velden J. Sequeira V, et al. Among authors: helmes m. J Physiol. 2015 Sep 1;593(17):3899-916. doi: 10.1113/JP270354. Epub 2015 Jul 14. J Physiol. 2015. PMID: 26096258 Free PMC article.

10

Mimicking the cardiac cycle in intact cardiomyocytes using diastolic and systolic force clamps; measuring power output.

Helmes M, Najafi A, Palmer BM, Breel E, Rijnveld N, Iannuzzi D, van der Velden J. Helmes M, et al. Cardiovasc Res. 2016 Jul 1;111(1):66-73. doi: 10.1093/cvr/cvw072. Epub 2016 Apr 1. Cardiovasc Res. 2016. PMID: 27037258 Free PMC article.

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