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5'isomiR-183-5p|+2 elicits tumor suppressor activity in a negative feedback loop with E2F1.
Li X, Michels BE, Tosun OE, Jung J, Kappes J, Ibing S, Nataraj NB, Sahay S, Schneider M, Wörner A, Becki C, Ishaque N, Feuerbach L, Heßling B, Helm D, Will R, Yarden Y, Müller-Decker K, Wiemann S, Körner C. Li X, et al. Among authors: helm d. J Exp Clin Cancer Res. 2022 Jun 2;41(1):190. doi: 10.1186/s13046-022-02380-8. J Exp Clin Cancer Res. 2022. PMID: 35655310 Free PMC article.
Comprehensive proteomic profiling of serum extracellular vesicles in patients with colorectal liver metastases identifies a signature for non-invasive risk stratification and early-response evaluation.
Lin K, Baenke F, Lai X, Schneider M, Helm D, Polster H, Rao VS, Ganig N, Wong FC, Seifert L, Seifert AM, Jahnke B, Kretschmann N, Ziemssen T, Klupp F, Schmidt T, Schneider M, Han Y, Weber TF, Plodeck V, Nebelung H, Schmitt N, Korell F, Köhler BC, Riediger C, Weitz J, Rahbari NN, Kahlert C. Lin K, et al. Among authors: helm d. Mol Cancer. 2022 Apr 1;21(1):91. doi: 10.1186/s12943-022-01562-4. Mol Cancer. 2022. PMID: 35365178 Free PMC article. No abstract available.
Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteins.
Pechincha C, Groessl S, Kalis R, de Almeida M, Zanotti A, Wittmann M, Schneider M, de Campos RP, Rieser S, Brandstetter M, Schleiffer A, Müller-Decker K, Helm D, Jabs S, Haselbach D, Lemberg MK, Zuber J, Palm W. Pechincha C, et al. Among authors: helm d. Science. 2022 Oct 7;378(6615):eabn5637. doi: 10.1126/science.abn5637. Epub 2022 Oct 7. Science. 2022. PMID: 36074822
Proteomic Analyses of Fibroblast- and Serum-Derived Exosomes Identify QSOX1 as a Marker for Non-invasive Detection of Colorectal Cancer.
Ganig N, Baenke F, Thepkaysone ML, Lin K, Rao VS, Wong FC, Polster H, Schneider M, Helm D, Pecqueux M, Seifert AM, Seifert L, Weitz J, Rahbari NN, Kahlert C. Ganig N, et al. Among authors: helm d. Cancers (Basel). 2021 Mar 17;13(6):1351. doi: 10.3390/cancers13061351. Cancers (Basel). 2021. PMID: 33802764 Free PMC article.
A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver.
Inverso D, Shi J, Lee KH, Jakab M, Ben-Moshe S, Kulkarni SR, Schneider M, Wang G, Komeili M, Vélez PA, Riedel M, Spegg C, Ruppert T, Schaeffer-Reiss C, Helm D, Singh I, Boutros M, Chintharlapalli S, Heikenwalder M, Itzkovitz S, Augustin HG. Inverso D, et al. Among authors: helm d. Dev Cell. 2021 Jun 7;56(11):1677-1693.e10. doi: 10.1016/j.devcel.2021.05.001. Epub 2021 May 25. Dev Cell. 2021. PMID: 34038707 Free PMC article.
Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions.
Schöpf J, Uhrig S, Heilig CE, Lee KS, Walther T, Carazzato A, Dobberkau AM, Weichenhan D, Plass C, Hartmann M, Diwan GD, Carrero ZI, Ball CR, Hohl T, Kindler T, Rudolph-Hähnel P, Helm D, Schneider M, Nilsson A, Øra I, Imle R, Banito A, Russell RB, Jones BC, Lipka DB, Glimm H, Hübschmann D, Hartmann W, Fröhling S, Scholl C. Schöpf J, et al. Among authors: helm d. Nat Commun. 2024 Jan 2;15(1):51. doi: 10.1038/s41467-023-44360-2. Nat Commun. 2024. PMID: 38168093 Free PMC article.
Proteome activity landscapes of tumor cell lines determine drug responses.
Frejno M, Meng C, Ruprecht B, Oellerich T, Scheich S, Kleigrewe K, Drecoll E, Samaras P, Hogrebe A, Helm D, Mergner J, Zecha J, Heinzlmeir S, Wilhelm M, Dorn J, Kvasnicka HM, Serve H, Weichert W, Kuster B. Frejno M, et al. Among authors: helm d. Nat Commun. 2020 Jul 20;11(1):3639. doi: 10.1038/s41467-020-17336-9. Nat Commun. 2020. PMID: 32686665 Free PMC article.
226 results