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Iron regulatory protein (IRP)-mediated iron homeostasis is critical for neutrophil development and differentiation in the bone marrow.
Bonadonna M, Altamura S, Tybl E, Palais G, Qatato M, Polycarpou-Schwarz M, Schneider M, Kalk C, Rüdiger W, Ertl A, Anstee N, Bogeska R, Helm D, Milsom MD, Galy B. Bonadonna M, et al. Among authors: helm d. Sci Adv. 2022 Oct 7;8(40):eabq4469. doi: 10.1126/sciadv.abq4469. Epub 2022 Oct 5. Sci Adv. 2022. PMID: 36197975 Free PMC article.
Thermal proteome profiling for interrogating protein interactions.
Mateus A, Kurzawa N, Becher I, Sridharan S, Helm D, Stein F, Typas A, Savitski MM. Mateus A, et al. Among authors: helm d. Mol Syst Biol. 2020 Mar;16(3):e9232. doi: 10.15252/msb.20199232. Mol Syst Biol. 2020. PMID: 32133759 Free PMC article. Review.
Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics.
Helm D, Vissers JP, Hughes CJ, Hahne H, Ruprecht B, Pachl F, Grzyb A, Richardson K, Wildgoose J, Maier SK, Marx H, Wilhelm M, Becher I, Lemeer S, Bantscheff M, Langridge JI, Kuster B. Helm D, et al. Mol Cell Proteomics. 2014 Dec;13(12):3709-15. doi: 10.1074/mcp.M114.041038. Epub 2014 Aug 8. Mol Cell Proteomics. 2014. PMID: 25106551 Free PMC article.
Chemical Proteomics Reveals Ferrochelatase as a Common Off-target of Kinase Inhibitors.
Klaeger S, Gohlke B, Perrin J, Gupta V, Heinzlmeir S, Helm D, Qiao H, Bergamini G, Handa H, Savitski MM, Bantscheff M, Médard G, Preissner R, Kuster B. Klaeger S, et al. Among authors: helm d. ACS Chem Biol. 2016 May 20;11(5):1245-54. doi: 10.1021/acschembio.5b01063. Epub 2016 Feb 25. ACS Chem Biol. 2016. PMID: 26863403
Proteomic Analyses of Fibroblast- and Serum-Derived Exosomes Identify QSOX1 as a Marker for Non-invasive Detection of Colorectal Cancer.
Ganig N, Baenke F, Thepkaysone ML, Lin K, Rao VS, Wong FC, Polster H, Schneider M, Helm D, Pecqueux M, Seifert AM, Seifert L, Weitz J, Rahbari NN, Kahlert C. Ganig N, et al. Among authors: helm d. Cancers (Basel). 2021 Mar 17;13(6):1351. doi: 10.3390/cancers13061351. Cancers (Basel). 2021. PMID: 33802764 Free PMC article.
226 results