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Histamine and T helper cytokine-driven epithelial barrier dysfunction in allergic rhinitis.
Steelant B, Seys SF, Van Gerven L, Van Woensel M, Farré R, Wawrzyniak P, Kortekaas Krohn I, Bullens DM, Talavera K, Raap U, Boon L, Akdis CA, Boeckxstaens G, Ceuppens JL, Hellings PW. Steelant B, et al. Among authors: hellings pw. J Allergy Clin Immunol. 2018 Mar;141(3):951-963.e8. doi: 10.1016/j.jaci.2017.08.039. Epub 2017 Oct 23. J Allergy Clin Immunol. 2018. PMID: 29074456 Free article. Clinical Trial.
Capsaicin treatment reduces nasal hyperreactivity and transient receptor potential cation channel subfamily V, receptor 1 (TRPV1) overexpression in patients with idiopathic rhinitis.
Van Gerven L, Alpizar YA, Wouters MM, Hox V, Hauben E, Jorissen M, Boeckxstaens G, Talavera K, Hellings PW. Van Gerven L, et al. Among authors: hellings pw. J Allergy Clin Immunol. 2014 May;133(5):1332-9, 1339.e1-3. doi: 10.1016/j.jaci.2013.08.026. Epub 2013 Oct 15. J Allergy Clin Immunol. 2014. PMID: 24139494
Impaired barrier function in patients with house dust mite-induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression.
Steelant B, Farré R, Wawrzyniak P, Belmans J, Dekimpe E, Vanheel H, Van Gerven L, Kortekaas Krohn I, Bullens DMA, Ceuppens JL, Akdis CA, Boeckxstaens G, Seys SF, Hellings PW. Steelant B, et al. Among authors: hellings pw. J Allergy Clin Immunol. 2016 Apr;137(4):1043-1053.e5. doi: 10.1016/j.jaci.2015.10.050. Epub 2016 Feb 2. J Allergy Clin Immunol. 2016. PMID: 26846377 Free article. Clinical Trial.
Enhanced chemosensory sensitivity in patients with idiopathic rhinitis and its reversal by nasal capsaicin treatment.
Van Gerven L, Alpizar YA, Steelant B, Callebaut I, Kortekaas Krohn I, Wouters M, Vermeulen F, Boeckxstaens G, Talavera K, Hellings PW. Van Gerven L, et al. Among authors: hellings pw. J Allergy Clin Immunol. 2017 Aug;140(2):437-446.e2. doi: 10.1016/j.jaci.2017.03.014. Epub 2017 Apr 4. J Allergy Clin Immunol. 2017. PMID: 28389389 Clinical Trial.
Blocking histone deacetylase activity as a novel target for epithelial barrier defects in patients with allergic rhinitis.
Steelant B, Wawrzyniak P, Martens K, Jonckheere AC, Pugin B, Schrijvers R, Bullens DM, Vanoirbeek JA, Krawczyk K, Dreher A, Akdis CA, Hellings PW. Steelant B, et al. Among authors: hellings pw. J Allergy Clin Immunol. 2019 Nov;144(5):1242-1253.e7. doi: 10.1016/j.jaci.2019.04.027. Epub 2019 May 11. J Allergy Clin Immunol. 2019. PMID: 31082457
Epithelial barriers in allergy and asthma.
Hellings PW, Steelant B. Hellings PW, et al. J Allergy Clin Immunol. 2020 Jun;145(6):1499-1509. doi: 10.1016/j.jaci.2020.04.010. J Allergy Clin Immunol. 2020. PMID: 32507228 Free PMC article. Review.
Epithelial and sensory mechanisms of nasal hyperreactivity.
Velasco E, Delicado-Miralles M, Hellings PW, Gallar J, Van Gerven L, Talavera K. Velasco E, et al. Among authors: hellings pw. Allergy. 2022 May;77(5):1450-1463. doi: 10.1111/all.15259. Epub 2022 Feb 26. Allergy. 2022. PMID: 35174893 Review.
315 results