Helland T - Search Results

1

Low Z-4OHtam concentrations are associated with adverse clinical outcome among early stage premenopausal breast cancer patients treated with adjuvant tamoxifen.

Helland T, Naume B, Hustad S, Bifulco E, Kvaløy JT, Saetersdal AB, Synnestvedt M, Lende TH, Gilje B, Mjaaland I, Weyde K, Blix ES, Wiedswang G, Borgen E, Hertz DL, Janssen EAM, Mellgren G, Søiland H. Helland T, et al. Mol Oncol. 2021 Apr;15(4):957-967. doi: 10.1002/1878-0261.12865. Epub 2020 Dec 14. Mol Oncol. 2021. PMID: 33252186 Free PMC article.

2

Downregulation of steroid receptor coactivator-2 modulates estrogen-responsive genes and stimulates proliferation of mcf-7 breast cancer cells.

Fenne IS, Helland T, Flågeng MH, Dankel SN, Mellgren G, Sagen JV. Fenne IS, et al. Among authors: helland t. PLoS One. 2013 Jul 30;8(7):e70096. doi: 10.1371/journal.pone.0070096. Print 2013. PLoS One. 2013. PMID: 23936147 Free PMC article.

3

The active tamoxifen metabolite endoxifen (4OHNDtam) strongly down-regulates cytokeratin 6 (CK6) in MCF-7 breast cancer cells.

Helland T, Gjerde J, Dankel S, Fenne IS, Skartveit L, Drangevåg A, Bozickovic O, Flågeng MH, Søiland H, Mellgren G, Lien EA. Helland T, et al. PLoS One. 2015 Apr 13;10(4):e0122339. doi: 10.1371/journal.pone.0122339. eCollection 2015. PLoS One. 2015. PMID: 25867603 Free PMC article.

4

Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients.

Helland T, Henne N, Bifulco E, Naume B, Borgen E, Kristensen VN, Kvaløy JT, Lash TL, Alnæs GIG, van Schaik RH, Janssen EAM, Hustad S, Lien EA, Mellgren G, Søiland H. Helland T, et al. Breast Cancer Res. 2017 Nov 28;19(1):125. doi: 10.1186/s13058-017-0916-4. Breast Cancer Res. 2017. PMID: 29183390 Free PMC article.

5

A novel SRC-2-dependent regulation of epithelial-mesenchymal transition in breast cancer cells.

Bozickovic O, Skartveit L, Engelsen AST, Helland T, Jonsdottir K, Flågeng MH, Fenne IS, Janssen E, Lorens JB, Bjørkhaug L, Sagen JV, Mellgren G. Bozickovic O, et al. Among authors: helland t. J Steroid Biochem Mol Biol. 2019 Jan;185:57-70. doi: 10.1016/j.jsbmb.2018.07.011. Epub 2018 Jul 23. J Steroid Biochem Mol Biol. 2019. PMID: 30048685

6

Drug monitoring of tamoxifen metabolites predicts vaginal dryness and verifies a low discontinuation rate from the Norwegian Prescription Database.

Helland T, Hagen KB, Haugstøyl ME, Kvaløy JT, Lunde S, Lode K, Lind RA, Gripsrud BH, Jonsdottir K, Gjerde J, Bifulco E, Hustad S, Jonassen J, Aas T, Lende TH, Lien EA, Janssen EAM, Søiland H, Mellgren G. Helland T, et al. Breast Cancer Res Treat. 2019 Aug;177(1):185-195. doi: 10.1007/s10549-019-05294-w. Epub 2019 May 29. Breast Cancer Res Treat. 2019. PMID: 31144152

7

First-in-human pharmacokinetics of tamoxifen and its metabolites in the milk of a lactating mother: a case study.

Peccatori FA, Codacci-Pisanelli G, Mellgren G, Buonomo B, Baldassarre E, Lien EA, Bifulco E, Hustad S, Zachariassen E, Johansson H, Helland T. Peccatori FA, et al. Among authors: helland t. ESMO Open. 2020 Oct;5(5):e000859. doi: 10.1136/esmoopen-2020-000859. ESMO Open. 2020. PMID: 33115771 Free PMC article.

8

Association of CYP2D6 genotype and tamoxifen metabolites with breast cancer recurrence in a low-dose trial.

DeCensi A, Johansson H, Helland T, Puntoni M, Macis D, Aristarco V, Caviglia S, Webber TB, Briata IM, D'Amico M, Serrano D, Guerrieri-Gonzaga A, Bifulco E, Hustad S, Søiland H, Boni L, Bonanni B, Mellgren G. DeCensi A, et al. Among authors: helland t. NPJ Breast Cancer. 2021 Mar 25;7(1):34. doi: 10.1038/s41523-021-00236-6. NPJ Breast Cancer. 2021. PMID: 33767162 Free PMC article.

9

Generating a Precision Endoxifen Prediction Algorithm to Advance Personalized Tamoxifen Treatment in Patients with Breast Cancer.

Helland T, Alsomairy S, Lin C, Søiland H, Mellgren G, Hertz DL. Helland T, et al. J Pers Med. 2021 Mar 13;11(3):201. doi: 10.3390/jpm11030201. J Pers Med. 2021. PMID: 33805613 Free PMC article. Review.

10

Effect of Genetic Variability in 20 Pharmacogenes on Concentrations of Tamoxifen and Its Metabolites.

Chen Y, Marcath LA, Eliassen FM, Lende TH, Soiland H, Mellgren G, Helland T, Hertz DL. Chen Y, et al. Among authors: helland t. J Pers Med. 2021 Jun 4;11(6):507. doi: 10.3390/jpm11060507. J Pers Med. 2021. PMID: 34199712 Free PMC article.

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