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Nonviral delivery of self-amplifying RNA vaccines.
Geall AJ, Verma A, Otten GR, Shaw CA, Hekele A, Banerjee K, Cu Y, Beard CW, Brito LA, Krucker T, O'Hagan DT, Singh M, Mason PW, Valiante NM, Dormitzer PR, Barnett SW, Rappuoli R, Ulmer JB, Mandl CW. Geall AJ, et al. Among authors: hekele a. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14604-9. doi: 10.1073/pnas.1209367109. Epub 2012 Aug 20. Proc Natl Acad Sci U S A. 2012. PMID: 22908294 Free PMC article.
A cationic nanoemulsion for the delivery of next-generation RNA vaccines.
Brito LA, Chan M, Shaw CA, Hekele A, Carsillo T, Schaefer M, Archer J, Seubert A, Otten GR, Beard CW, Dey AK, Lilja A, Valiante NM, Mason PW, Mandl CW, Barnett SW, Dormitzer PR, Ulmer JB, Singh M, O'Hagan DT, Geall AJ. Brito LA, et al. Among authors: hekele a. Mol Ther. 2014 Dec;22(12):2118-2129. doi: 10.1038/mt.2014.133. Epub 2014 Jul 16. Mol Ther. 2014. PMID: 25027661 Free PMC article.
Rapidly produced SAM(®) vaccine against H7N9 influenza is immunogenic in mice.
Hekele A, Bertholet S, Archer J, Gibson DG, Palladino G, Brito LA, Otten GR, Brazzoli M, Buccato S, Bonci A, Casini D, Maione D, Qi ZQ, Gill JE, Caiazza NC, Urano J, Hubby B, Gao GF, Shu Y, De Gregorio E, Mandl CW, Mason PW, Settembre EC, Ulmer JB, Craig Venter J, Dormitzer PR, Rappuoli R, Geall AJ. Hekele A, et al. Emerg Microbes Infect. 2013 Aug;2(8):e52. doi: 10.1038/emi.2013.54. Epub 2013 Aug 14. Emerg Microbes Infect. 2013. PMID: 26038486 Free PMC article.
Mutations at positions 186 and 194 in the HA gene of the 2009 H1N1 pandemic influenza virus improve replication in cell culture and eggs.
Suphaphiphat P, Franti M, Hekele A, Lilja A, Spencer T, Settembre E, Palmer G, Crotta S, Tuccino AB, Keiner B, Trusheim H, Balabanis K, Sackal M, Rothfeder M, Mandl CW, Dormitzer PR, Mason PW. Suphaphiphat P, et al. Among authors: hekele a. Virol J. 2010 Jul 14;7:157. doi: 10.1186/1743-422X-7-157. Virol J. 2010. PMID: 20630098 Free PMC article.
Integration of a CD19 CAR into the TCR Alpha Chain Locus Streamlines Production of Allogeneic Gene-Edited CAR T Cells.
MacLeod DT, Antony J, Martin AJ, Moser RJ, Hekele A, Wetzel KJ, Brown AE, Triggiano MA, Hux JA, Pham CD, Bartsevich VV, Turner CA, Lape J, Kirkland S, Beard CW, Smith J, Hirsch ML, Nicholson MG, Jantz D, McCreedy B. MacLeod DT, et al. Among authors: hekele a. Mol Ther. 2017 Apr 5;25(4):949-961. doi: 10.1016/j.ymthe.2017.02.005. Epub 2017 Feb 23. Mol Ther. 2017. PMID: 28237835 Free PMC article.
23 results