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Identification of aberrant luminal progenitors and mTORC1 as a potential breast cancer prevention target in BRCA2 mutation carriers.
Nat Cell Biol. 2024 Jan;26(1):138-152. doi: 10.1038/s41556-023-01315-5. Epub 2024 Jan 12.
Nat Cell Biol. 2024.
PMID: 38216737
Correction to: The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells.
Wang Z, Hu H, Heitink L, Rogers K, You Y, Tan T, Suen CLW, Garnham A, Chen H, Lieschke E, Diepstraten ST, Chang C, Chen T, Moujalled D, Sutherland K, Lessene G, Sieber OM, Visvader J, Kelly GL, Strasser A.
Wang Z, et al. Among authors: heitink l.
Cell Death Differ. 2023 Apr;30(4):1096. doi: 10.1038/s41418-023-01137-w.
Cell Death Differ. 2023.
PMID: 36828917
Free PMC article.
No abstract available.
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The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells.
Wang Z, Hu H, Heitink L, Rogers K, You Y, Tan T, Suen CLW, Garnham A, Chen H, Lieschke E, Diepstraten ST, Chang C, Chen T, Moujalled D, Sutherland K, Lessene G, Sieber OM, Visvader J, Kelly GL, Strasser A.
Wang Z, et al. Among authors: heitink l.
Cell Death Differ. 2023 Apr;30(4):1033-1046. doi: 10.1038/s41418-023-01122-3. Epub 2023 Feb 4.
Cell Death Differ. 2023.
PMID: 36739334
Free PMC article.
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In vivo genome-editing screen identifies tumor suppressor genes that cooperate with Trp53 loss during mammary tumorigenesis.
Heitink L, Whittle JR, Vaillant F, Capaldo BD, Dekkers JF, Dawson CA, Milevskiy MJG, Surgenor E, Tsai M, Chen HR, Christie M, Chen Y, Smyth GK, Herold MJ, Strasser A, Lindeman GJ, Visvader JE.
Heitink L, et al.
Mol Oncol. 2022 Mar;16(5):1119-1131. doi: 10.1002/1878-0261.13179. Epub 2022 Jan 26.
Mol Oncol. 2022.
PMID: 35000262
Free PMC article.
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LEFTY1 Is a Dual-SMAD Inhibitor that Promotes Mammary Progenitor Growth and Tumorigenesis.
Zabala M, Lobo NA, Antony J, Heitink LS, Gulati GS, Lam J, Parashurama N, Sanchez K, Adorno M, Sikandar SS, Kuo AH, Qian D, Kalisky T, Sim S, Li L, Dirbas FM, Somlo G, Newman A, Quake SR, Clarke MF.
Zabala M, et al. Among authors: heitink ls.
Cell Stem Cell. 2020 Aug 6;27(2):284-299.e8. doi: 10.1016/j.stem.2020.06.017. Epub 2020 Jul 20.
Cell Stem Cell. 2020.
PMID: 32693087
Free article.
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Persistent repair intermediates induce senescence.
Feringa FM, Raaijmakers JA, Hadders MA, Vaarting C, Macurek L, Heitink L, Krenning L, Medema RH.
Feringa FM, et al. Among authors: heitink l.
Nat Commun. 2018 Sep 25;9(1):3923. doi: 10.1038/s41467-018-06308-9.
Nat Commun. 2018.
PMID: 30254262
Free PMC article.
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