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Dual SGLT-1 and SGLT-2 inhibition improves left atrial dysfunction in HFpEF.
Bode D, Semmler L, Wakula P, Hegemann N, Primessnig U, Beindorff N, Powell D, Dahmen R, Ruetten H, Oeing C, Alogna A, Messroghli D, Pieske BM, Heinzel FR, Hohendanner F. Bode D, et al. Among authors: heinzel fr. Cardiovasc Diabetol. 2021 Jan 7;20(1):7. doi: 10.1186/s12933-020-01208-z. Cardiovasc Diabetol. 2021. PMID: 33413413 Free PMC article.
cAMP- and Ca²(+) /calmodulin-dependent protein kinases mediate inotropic, lusitropic and arrhythmogenic effects of urocortin 2 in mouse ventricular myocytes.
Yang LZ, Kockskämper J, Khan S, Suarez J, Walther S, Doleschal B, Unterer G, Khafaga M, Mächler H, Heinzel FR, Dillmann WH, Pieske B, Spiess J. Yang LZ, et al. Among authors: heinzel fr. Br J Pharmacol. 2011 Jan;162(2):544-56. doi: 10.1111/j.1476-5381.2010.01067.x. Br J Pharmacol. 2011. PMID: 20942811 Free PMC article.
JTV519 (K201) reduces sarcoplasmic reticulum Ca²⁺ leak and improves diastolic function in vitro in murine and human non-failing myocardium.
Sacherer M, Sedej S, Wakuła P, Wallner M, Vos MA, Kockskämper J, Stiegler P, Sereinigg M, von Lewinski D, Antoons G, Pieske BM, Heinzel FR; CONTICA investigators. Sacherer M, et al. Among authors: heinzel fr. Br J Pharmacol. 2012 Oct;167(3):493-504. doi: 10.1111/j.1476-5381.2012.01995.x. Br J Pharmacol. 2012. PMID: 22509897 Free PMC article.
Intracellular dyssynchrony of diastolic cytosolic [Ca²⁺] decay in ventricular cardiomyocytes in cardiac remodeling and human heart failure.
Hohendanner F, Ljubojević S, MacQuaide N, Sacherer M, Sedej S, Biesmans L, Wakula P, Platzer D, Sokolow S, Herchuelz A, Antoons G, Sipido K, Pieske B, Heinzel FR. Hohendanner F, et al. Among authors: heinzel fr. Circ Res. 2013 Aug 16;113(5):527-38. doi: 10.1161/CIRCRESAHA.113.300895. Epub 2013 Jul 3. Circ Res. 2013. PMID: 23825358
107 results