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Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.
Becquemont L, Glaeser H, Drescher S, Hitzl M, Simon N, Murdter TE, Heinkele G, Hofmann U, Schaefer C, Burk O, Verstuyft C, Eichelbaum M, Fromm MF. Becquemont L, et al. Among authors: heinkele g. Clin Pharmacol Ther. 2006 May;79(5):449-60. doi: 10.1016/j.clpt.2006.01.005. Epub 2006 Apr 11. Clin Pharmacol Ther. 2006. PMID: 16678547 Clinical Trial.
Stereoselective quantification of methadone and a d(6)-labeled isotopomer using high performance liquid chromatography-atmospheric pressure chemical ionization mass-spectrometry: application to a pharmacokinetic study in a methadone maintained subject.
Foster DJ, Morton EB, Heinkele G, Mürdter TE, Somogyi AA. Foster DJ, et al. Among authors: heinkele g. Ther Drug Monit. 2006 Aug;28(4):559-67. doi: 10.1097/00007691-200608000-00012. Ther Drug Monit. 2006. PMID: 16885725 Clinical Trial.
Activity levels of tamoxifen metabolites at the estrogen receptor and the impact of genetic polymorphisms of phase I and II enzymes on their concentration levels in plasma.
Mürdter TE, Schroth W, Bacchus-Gerybadze L, Winter S, Heinkele G, Simon W, Fasching PA, Fehm T; German Tamoxifen and AI Clinicians Group; Eichelbaum M, Schwab M, Brauch H. Mürdter TE, et al. Among authors: heinkele g. Clin Pharmacol Ther. 2011 May;89(5):708-17. doi: 10.1038/clpt.2011.27. Epub 2011 Mar 30. Clin Pharmacol Ther. 2011. PMID: 21451508 Clinical Trial.
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