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Strategies for the modulation of phase II metabolism in a series of PKCε inhibitors.
Clemens JJ, Coon T, Busch BB, Asgian JL, Hudson S, Termin A, Flores TB, Tran D, Chiang P, Sperry S, Gross R, Abt J, Heim R, Lechner S, Twin H, Studley J, Brenchley G, Collier PN, Pierard F, Miller A, Mak C, Dvornikovs V, Jimenez JM, Stamos D. Clemens JJ, et al. Among authors: heim r. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3398-402. doi: 10.1016/j.bmcl.2014.05.082. Epub 2014 Jun 5. Bioorg Med Chem Lett. 2014. PMID: 24939756
Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis.
Migliore M Dr, Pontis S Dr, Fuentes de Arriba AL, Realini N, Torrente E, Armirotti A, Romeo E, Di Martino S, Russo D, Pizzirani D, Summa M, Lanfranco M, Ottonello G, Busquet P, Jung KM, Garcia-Guzman M, Heim R, Scarpelli R, Piomelli D. Migliore M Dr, et al. Among authors: heim r. Angew Chem Int Ed Engl. 2016 Sep 5;55(37):11193-11197. doi: 10.1002/anie.201603746. Epub 2016 Jul 12. Angew Chem Int Ed Engl. 2016. PMID: 27404798 Free PMC article.
Cancer-targeted photoimmunotherapy induces antitumor immunity and can be augmented by anti-PD-1 therapy for durable anticancer responses in an immunologically active murine tumor model.
Hsu MA, Okamura SM, De Magalhaes Filho CD, Bergeron DM, Rodriguez A, West M, Yadav D, Heim R, Fong JJ, Garcia-Guzman M. Hsu MA, et al. Among authors: heim r. Cancer Immunol Immunother. 2023 Jan;72(1):151-168. doi: 10.1007/s00262-022-03239-9. Epub 2022 Jul 1. Cancer Immunol Immunother. 2023. PMID: 35776159 Free PMC article.
Near infra-red photoimmunotherapy with anti-CEA-IR700 results in extensive tumor lysis and a significant decrease in tumor burden in orthotopic mouse models of pancreatic cancer.
Maawy AA, Hiroshima Y, Zhang Y, Heim R, Makings L, Garcia-Guzman M, Luiken GA, Kobayashi H, Hoffman RM, Bouvet M. Maawy AA, et al. Among authors: heim r. PLoS One. 2015 Mar 23;10(3):e0121989. doi: 10.1371/journal.pone.0121989. eCollection 2015. PLoS One. 2015. PMID: 25799218 Free PMC article.
Photoimmunotherapy Inhibits Tumor Recurrence After Surgical Resection on a Pancreatic Cancer Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model.
Hiroshima Y, Maawy A, Zhang Y, Guzman MG, Heim R, Makings L, Luiken GA, Kobayashi H, Tanaka K, Endo I, Hoffman RM, Bouvet M. Hiroshima Y, et al. Among authors: heim r. Ann Surg Oncol. 2015 Dec;22 Suppl 3(Suppl 3):S1469-74. doi: 10.1245/s10434-015-4553-9. Epub 2015 Apr 17. Ann Surg Oncol. 2015. PMID: 25893411 Free PMC article.
The Arctic Plant Aboveground Biomass Synthesis Dataset.
Berner LT, Orndahl KM, Rose M, Tamstorf M, Arndal MF, Alexander HD, Humphreys ER, Loranty MM, Ludwig SM, Nyman J, Juutinen S, Aurela M, Happonen K, Mikola J, Mack MC, Vankoughnett MR, Iversen CM, Salmon VG, Yang D, Kumar J, Grogan P, Danby RK, Scott NA, Olofsson J, Siewert MB, Deschamps L, Lévesque E, Maire V, Morneault A, Gauthier G, Gignac C, Boudreau S, Gaspard A, Kholodov A, Bret-Harte MS, Greaves HE, Walker D, Gregory FM, Michelsen A, Kumpula T, Villoslada M, Ylänne H, Luoto M, Virtanen T, Forbes BC, Hölzel N, Epstein H, Heim RJ, Bunn A, Holmes RM, Hung JKY, Natali SM, Virkkala AM, Goetz SJ. Berner LT, et al. Among authors: heim rj. Sci Data. 2024 Mar 20;11(1):305. doi: 10.1038/s41597-024-03139-w. Sci Data. 2024. PMID: 38509110 Free PMC article.
133 results