Heim JB - Search Results

1

Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics.

Heggelund JE, Mackenzie A, Martinsen T, Heim JB, Cheshev P, Bernardi A, Krengel U. Heggelund JE, et al. Among authors: heim jb. Sci Rep. 2017 May 24;7(1):2326. doi: 10.1038/s41598-017-02179-0. Sci Rep. 2017. PMID: 28539625 Free PMC article.

2

Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site.

Heim JB, Hodnik V, Heggelund JE, Anderluh G, Krengel U. Heim JB, et al. Sci Rep. 2019 Aug 22;9(1):12243. doi: 10.1038/s41598-019-48579-2. Sci Rep. 2019. PMID: 31439922 Free PMC article.

3

Specificity of Escherichia coli Heat-Labile Enterotoxin Investigated by Single-Site Mutagenesis and Crystallography.

Heggelund JE, Heim JB, Bajc G, Hodnik V, Anderluh G, Krengel U. Heggelund JE, et al. Among authors: heim jb. Int J Mol Sci. 2019 Feb 6;20(3):703. doi: 10.3390/ijms20030703. Int J Mol Sci. 2019. PMID: 30736336 Free PMC article.

4

Holotoxin disassembly by protein disulfide isomerase is less efficient for Escherichia coli heat-labile enterotoxin than cholera toxin.

Serrano A, Guyette JL, Heim JB, Taylor M, Cherubin P, Krengel U, Teter K, Tatulian SA. Serrano A, et al. Among authors: heim jb. Sci Rep. 2022 Jan 7;12(1):34. doi: 10.1038/s41598-021-03939-9. Sci Rep. 2022. PMID: 34997016 Free PMC article.

5

Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp.

Burschowsky D, Thorbjørnsrud HV, Heim JB, Fahrig-Kamarauskaitė JR, Würth-Roderer K, Kast P, Krengel U. Burschowsky D, et al. Among authors: heim jb. Biochemistry. 2018 Feb 6;57(5):557-573. doi: 10.1021/acs.biochem.7b01018. Epub 2017 Dec 21. Biochemistry. 2018. PMID: 29178787

6

Vinylogous chain branching catalysed by a dedicated polyketide synthase module.

Bretschneider T, Heim JB, Heine D, Winkler R, Busch B, Kusebauch B, Stehle T, Zocher G, Hertweck C. Bretschneider T, et al. Among authors: heim jb. Nature. 2013 Oct 3;502(7469):124-8. doi: 10.1038/nature12588. Epub 2013 Sep 18. Nature. 2013. PMID: 24048471

7

Structure-based engineering increased the catalytic turnover rate of a novel phenazine prenyltransferase.

Zocher G, Saleh O, Heim JB, Herbst DA, Heide L, Stehle T. Zocher G, et al. Among authors: heim jb. PLoS One. 2012;7(10):e48427. doi: 10.1371/journal.pone.0048427. Epub 2012 Oct 31. PLoS One. 2012. PMID: 23119011 Free PMC article.

8

Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.

Heim JB, Squirewell EJ, Neu A, Zocher G, Sominidi-Damodaran S, Wyles SP, Nikolova E, Behrendt N, Saunte DM, Lock-Andersen J, Gaonkar KS, Yan H, Sarkaria JN, Krendel M, van Deursen J, Sprangers R, Stehle T, Böttcher RT, Lee JH, Ordog T, Meves A. Heim JB, et al. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3933-3938. doi: 10.1073/pnas.1614894114. Epub 2017 Mar 27. Proc Natl Acad Sci U S A. 2017. PMID: 28348210 Free PMC article.

9

FAK auto-phosphorylation site tyrosine 397 is required for development but dispensable for normal skin homeostasis.

Heim JB, McDonald CA, Wyles SP, Sominidi-Damodaran S, Squirewell EJ, Li M, Motsonelidze C, Böttcher RT, van Deursen J, Meves A. Heim JB, et al. PLoS One. 2018 Jul 12;13(7):e0200558. doi: 10.1371/journal.pone.0200558. eCollection 2018. PLoS One. 2018. PMID: 30001432 Free PMC article.

10

Tumor Cell Adhesion As a Risk Factor for Sentinel Lymph Node Metastasis in Primary Cutaneous Melanoma.

Meves A, Nikolova E, Heim JB, Squirewell EJ, Cappel MA, Pittelkow MR, Otley CC, Behrendt N, Saunte DM, Lock-Andersen J, Schenck LA, Weaver AL, Suman VJ. Meves A, et al. Among authors: heim jb. J Clin Oncol. 2015 Aug 10;33(23):2509-15. doi: 10.1200/JCO.2014.60.7002. Epub 2015 Jul 6. J Clin Oncol. 2015. PMID: 26150443 Free PMC article.

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