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Procaspase-Activating Compound-1 Synergizes with TRAIL to Induce Apoptosis in Established Granulosa Cell Tumor Cell Line (KGN) and Explanted Patient Granulosa Cell Tumor Cells In Vitro.
Crosley P, Farkkila A, Jenner AL, Burlot C, Cardinal O, Potts KG, Agopsowicz K, Pihlajoki M, Heikinheimo M, Craig M, Fu Y, Hitt MM. Crosley P, et al. Among authors: heikinheimo m. Int J Mol Sci. 2021 Apr 29;22(9):4699. doi: 10.3390/ijms22094699. Int J Mol Sci. 2021. PMID: 33946730 Free PMC article.
Ovarian granulosa cell tumors in childhood.
Merras-Salmio L, Vettenranta K, Möttönen M, Heikinheimo M. Merras-Salmio L, et al. Among authors: heikinheimo m. Pediatr Hematol Oncol. 2002 Apr-May;19(3):145-56. doi: 10.1080/088800102753541297. Pediatr Hematol Oncol. 2002. PMID: 11936727 Review.
GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis.
Kyrönlahti A, Kauppinen M, Lind E, Unkila-Kallio L, Butzow R, Klefström J, Wilson DB, Anttonen M, Heikinheimo M. Kyrönlahti A, et al. Among authors: heikinheimo m. Endocr Relat Cancer. 2010 Jul 28;17(3):709-17. doi: 10.1677/ERC-10-0041. Print 2010 Sep. Endocr Relat Cancer. 2010. PMID: 20554787
Serum vascular endothelial growth factor A (VEGF) is elevated in patients with ovarian granulosa cell tumor (GCT), and VEGF inhibition by bevacizumab induces apoptosis in GCT in vitro.
Färkkilä A, Pihlajoki M, Tauriala H, Bützow R, Leminen A, Unkila-Kallio L, Heikinheimo M, Anttonen M. Färkkilä A, et al. Among authors: heikinheimo m. J Clin Endocrinol Metab. 2011 Dec;96(12):E1973-81. doi: 10.1210/jc.2011-1812. Epub 2011 Oct 12. J Clin Endocrinol Metab. 2011. PMID: 21994955
GATA4 is a critical regulator of gonadectomy-induced adrenocortical tumorigenesis in mice.
Krachulec J, Vetter M, Schrade A, Löbs AK, Bielinska M, Cochran R, Kyrönlahti A, Pihlajoki M, Parviainen H, Jay PY, Heikinheimo M, Wilson DB. Krachulec J, et al. Among authors: heikinheimo m. Endocrinology. 2012 Jun;153(6):2599-611. doi: 10.1210/en.2011-2135. Epub 2012 Mar 28. Endocrinology. 2012. PMID: 22461617 Free PMC article.
Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice.
Pihlajoki M, Gretzinger E, Cochran R, Kyrönlahti A, Schrade A, Hiller T, Sullivan L, Shoykhet M, Schoeller EL, Brooks MD, Heikinheimo M, Wilson DB. Pihlajoki M, et al. Among authors: heikinheimo m. Endocrinology. 2013 May;154(5):1754-67. doi: 10.1210/en.2012-1892. Epub 2013 Mar 7. Endocrinology. 2013. PMID: 23471215 Free PMC article.
Never underestimate the complexity of remodeling.
Pihlajoki M, Heikinheimo M, Wilson DB. Pihlajoki M, et al. Among authors: heikinheimo m. Endocrinology. 2013 Dec;154(12):4446-9. doi: 10.1210/en.2013-1982. Endocrinology. 2013. PMID: 24273232 No abstract available.
223 results