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Discovery of pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives as novel CDK2 inhibitors: synthesis, biological and molecular modeling investigations.
Nassar IF, Abdel Aal MT, El-Sayed WA, A E Shahin M, Elsakka EGE, Mokhtar MM, Hegazy M, Hagras M, Mandour AA, Ismail NSM. Nassar IF, et al. Among authors: hegazy m. RSC Adv. 2022 May 17;12(23):14865-14882. doi: 10.1039/d2ra01968j. eCollection 2022 May 12. RSC Adv. 2022. PMID: 35702208 Free PMC article.
Synthesis, biological evaluation, and in silico studies of new CDK2 inhibitors based on pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold with apoptotic activity.
Mandour AA, Nassar IF, Abdel Aal MT, Shahin MAE, El-Sayed WA, Hegazy M, Yehia AM, Ismail A, Hagras M, Elkaeed EB, Refaat HM, Ismail NSM. Mandour AA, et al. Among authors: hegazy m. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1957-1973. doi: 10.1080/14756366.2022.2086866. J Enzyme Inhib Med Chem. 2022. PMID: 35815597 Free PMC article.
miRNAs driving diagnosis, progression, and drug resistance in multiple myeloma.
Elkady MA, Yehia AM, Elsakka EGE, Abulsoud AI, Abdelmaksoud NM, Elshafei A, Elkhawaga SY, Ismail A, Mokhtar MM, El-Mahdy HA, Hegazy M, Elballal MS, Mohammed OA, El-Husseiny HM, Midan HM, El-Dakroury WA, Zewail MB, Abdel Mageed SS, Doghish AS. Elkady MA, et al. Among authors: hegazy m. Pathol Res Pract. 2023 Aug;248:154704. doi: 10.1016/j.prp.2023.154704. Epub 2023 Jul 22. Pathol Res Pract. 2023. PMID: 37499518 Review.
Discovery of New Uracil and Thiouracil Derivatives as Potential HDAC Inhibitors.
Elbatrawy OR, Hagras M, El Deeb MA, Agili F, Hegazy M, El-Husseiny AA, Mokhtar MM, Elkhawaga SY, Eissa IH, El-Kalyoubi S. Elbatrawy OR, et al. Among authors: hegazy m. Pharmaceuticals (Basel). 2023 Jul 6;16(7):966. doi: 10.3390/ph16070966. Pharmaceuticals (Basel). 2023. PMID: 37513878 Free PMC article.
592 results