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Error-corrected next generation sequencing - Promises and challenges for genotoxicity and cancer risk assessment.
Marchetti F, Cardoso R, Chen CL, Douglas GR, Elloway J, Escobar PA, Harper T Jr, Heflich RH, Kidd D, Lynch AM, Myers MB, Parsons BL, Salk JJ, Settivari RS, Smith-Roe SL, Witt KL, Yauk CL, Young R, Zhang S, Minocherhomji S. Marchetti F, et al. Among authors: heflich rh. Mutat Res Rev Mutat Res. 2023 Jul-Dec;792:108466. doi: 10.1016/j.mrrev.2023.108466. Epub 2023 Aug 27. Mutat Res Rev Mutat Res. 2023. PMID: 37643677 Free article. Review.
Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing.
Marchetti F, Cardoso R, Chen CL, Douglas GR, Elloway J, Escobar PA, Harper T Jr, Heflich RH, Kidd D, Lynch AM, Myers MB, Parsons BL, Salk JJ, Settivari RS, Smith-Roe SL, Witt KL, Yauk C, Young RR, Zhang S, Minocherhomji S. Marchetti F, et al. Among authors: heflich rh. Nat Rev Drug Discov. 2023 Mar;22(3):165-166. doi: 10.1038/d41573-023-00014-y. Nat Rev Drug Discov. 2023. PMID: 36646809 No abstract available.
Assessing the quality and making appropriate use of historical negative control data: A report of the International Workshop on Genotoxicity Testing (IWGT).
Dertinger SD, Li D, Beevers C, Douglas GR, Heflich RH, Lovell DP, Roberts DJ, Smith R, Uno Y, Williams A, Witt KL, Zeller A, Zhou C. Dertinger SD, et al. Among authors: heflich rh. Environ Mol Mutagen. 2023 Apr 25:10.1002/em.22541. doi: 10.1002/em.22541. Online ahead of print. Environ Mol Mutagen. 2023. PMID: 37097075 Review.
Interpretation of in vitro concentration-response data for risk assessment and regulatory decision-making: Report from the 2022 IWGT quantitative analysis expert working group meeting.
Beal MA, Chen G, Dearfield KL, Gi M, Gollapudi B, Heflich RH, Horibata K, Long AS, Lovell DP, Parsons BL, Pfuhler S, Wills J, Zeller A, Johnson G, White PA. Beal MA, et al. Among authors: heflich rh. Environ Mol Mutagen. 2023 Dec 19. doi: 10.1002/em.22582. Online ahead of print. Environ Mol Mutagen. 2023. PMID: 38115239 Review.
Revisiting the mutagenicity and genotoxicity of N-nitroso propranolol in bacterial and human in vitro assays.
Li X, Le Y, Seo JE, Guo X, Li Y, Chen S, Mittelstaedt RA, Moore N, Guerrero S, Sims A, King ST, Atrakchi AH, McGovern TJ, Davis-Bruno KL, Keire DA, Elespuru RK, Heflich RH, Mei N. Li X, et al. Among authors: heflich rh. Regul Toxicol Pharmacol. 2023 Jun;141:105410. doi: 10.1016/j.yrtph.2023.105410. Epub 2023 May 18. Regul Toxicol Pharmacol. 2023. PMID: 37210026
Key Challenges and Recommendations for In Vitro Testing of Tobacco Products for Regulatory Applications: Consideration of Test Materials and Exposure Parameters.
Moore MM, Abraham I, Ballantyne M, Behrsing H, Cao X, Clements J, Gaca M, Gillman G, Hashizume T, Heflich RH, Hurtado S, Jordan KG, Leverette R, McHugh D, Miller-Holt J, Phillips G, Recio L, Roy S, Scian M, Simms L, Smart DJ, Stankowski LF Jr, Tarran R, Thorne D, Weber E, Wieczorek R, Yoshino K, Curren R. Moore MM, et al. Among authors: heflich rh. Altern Lab Anim. 2023 Jan;51(1):55-79. doi: 10.1177/02611929221146536. Altern Lab Anim. 2023. PMID: 36821083
249 results