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Derivation of point of departure (PoD) estimates in genetic toxicology studies and their potential applications in risk assessment.
Johnson GE, Soeteman-Hernández LG, Gollapudi BB, Bodger OG, Dearfield KL, Heflich RH, Hixon JG, Lovell DP, MacGregor JT, Pottenger LH, Thompson CM, Abraham L, Thybaud V, Tanir JY, Zeiger E, van Benthem J, White PA. Johnson GE, et al. Among authors: heflich rh. Environ Mol Mutagen. 2014 Oct;55(8):609-23. doi: 10.1002/em.21870. Epub 2014 May 6. Environ Mol Mutagen. 2014. PMID: 24801602 Free PMC article.
The in vivo Pig-a assay: A report of the International Workshop On Genotoxicity Testing (IWGT) Workgroup.
Gollapudi BB, Lynch AM, Heflich RH, Dertinger SD, Dobrovolsky VN, Froetschl R, Horibata K, Kenyon MO, Kimoto T, Lovell DP, Stankowski LF Jr, White PA, Witt KL, Tanir JY. Gollapudi BB, et al. Among authors: heflich rh. Mutat Res Genet Toxicol Environ Mutagen. 2015 May 1;783:23-35. doi: 10.1016/j.mrgentox.2014.09.007. Epub 2014 Sep 26. Mutat Res Genet Toxicol Environ Mutagen. 2015. PMID: 25953398
Pig-a gene mutation database.
Shemansky JM, McDaniel LP, Klimas C, Dertinger SD, Dobrovolsky VN, Kimoto T, Horibata K, Polli JE, Heflich RH. Shemansky JM, et al. Among authors: heflich rh. Environ Mol Mutagen. 2019 Oct;60(8):759-762. doi: 10.1002/em.22298. Epub 2019 Jun 7. Environ Mol Mutagen. 2019. PMID: 31090953
Transgenic animal models in toxicology: historical perspectives and future outlook.
Boverhof DR, Chamberlain MP, Elcombe CR, Gonzalez FJ, Heflich RH, Hernández LG, Jacobs AC, Jacobson-Kram D, Luijten M, Maggi A, Manjanatha MG, Benthem Jv, Gollapudi BB. Boverhof DR, et al. Among authors: heflich rh. Toxicol Sci. 2011 Jun;121(2):207-33. doi: 10.1093/toxsci/kfr075. Epub 2011 Mar 29. Toxicol Sci. 2011. PMID: 21447610 Review.
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing.
Wang Y, Mittelstaedt RA, Wynne R, Chen Y, Cao X, Muskhelishvili L, Davis K, Robison TW, Sun W, Schmidt EK, Smith TH, Norgaard ZK, Valentine CC, Yaplee J, Williams LN, Salk JJ, Heflich RH. Wang Y, et al. Among authors: heflich rh. Environ Mol Mutagen. 2021 Jun;62(5):306-318. doi: 10.1002/em.22444. Epub 2021 Jun 14. Environ Mol Mutagen. 2021. PMID: 34050964 Free PMC article.
249 results