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Mutations in FUS lead to synaptic dysregulation in ALS-iPSC derived neurons.
Stem Cell Reports. 2024 Feb 13;19(2):187-195. doi: 10.1016/j.stemcr.2023.12.007. Epub 2024 Jan 18.
Stem Cell Reports. 2024.
PMID: 38242131
Free PMC article.
The Use of Stem Cells to Model Amyotrophic Lateral Sclerosis and Frontotemporal Dementia: From Basic Research to Regenerative Medicine.
Hedges EC, Mehler VJ, Nishimura AL.
Hedges EC, et al.
Stem Cells Int. 2016;2016:9279516. doi: 10.1155/2016/9279516. Epub 2016 Feb 7.
Stem Cells Int. 2016.
PMID: 26966440
Free PMC article.
Review.
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Generation of six induced pluripotent stem cell lines from patients with amyotrophic lateral sclerosis with associated genetic mutations in either FUS or ANXA11.
Hedges EC, Topp S, Shaw CE, Nishimura AL.
Hedges EC, et al.
Stem Cell Res. 2021 Apr;52:102246. doi: 10.1016/j.scr.2021.102246. Epub 2021 Feb 12.
Stem Cell Res. 2021.
PMID: 33610019
Free PMC article.
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Generation of an Open-Access Patient-Derived iPSC Biobank for Amyotrophic Lateral Sclerosis Disease Modelling.
Hedges EC, Cocks G, Shaw CE, Nishimura AL.
Hedges EC, et al.
Genes (Basel). 2023 May 18;14(5):1108. doi: 10.3390/genes14051108.
Genes (Basel). 2023.
PMID: 37239468
Free PMC article.
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Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection.
Yang F, Beltran-Lobo P, Sung K, Goldrick C, Croft CL, Nishimura A, Hedges E, Mahiddine F, Troakes C, Golde TE, Perez-Nievas BG, Hanger DP, Noble W, Jimenez-Sanchez M.
Yang F, et al.
Sci Adv. 2024 Mar 22;10(12):eadk9884. doi: 10.1126/sciadv.adk9884. Epub 2024 Mar 20.
Sci Adv. 2024.
PMID: 38507480
Free PMC article.
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Telomere length and human hippocampal neurogenesis.
Palmos AB, Duarte RRR, Smeeth DM, Hedges EC, Nixon DF, Thuret S, Powell TR.
Palmos AB, et al. Among authors: hedges ec.
Neuropsychopharmacology. 2020 Dec;45(13):2239-2247. doi: 10.1038/s41386-020-00863-w. Epub 2020 Sep 13.
Neuropsychopharmacology. 2020.
PMID: 32920596
Free PMC article.
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Lithium treatment and human hippocampal neurogenesis.
Palmos AB, Duarte RRR, Smeeth DM, Hedges EC, Nixon DF, Thuret S, Powell TR.
Palmos AB, et al. Among authors: hedges ec.
Transl Psychiatry. 2021 Oct 30;11(1):555. doi: 10.1038/s41398-021-01695-y.
Transl Psychiatry. 2021.
PMID: 34718328
Free PMC article.
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