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Dietary supplementation with docosahexaenoic acid, but not eicosapentaenoic acid, dramatically alters cardiac mitochondrial phospholipid fatty acid composition and prevents permeability transition.
Khairallah RJ, Sparagna GC, Khanna N, O'Shea KM, Hecker PA, Kristian T, Fiskum G, Des Rosiers C, Polster BM, Stanley WC. Khairallah RJ, et al. Among authors: hecker pa. Biochim Biophys Acta. 2010 Aug;1797(8):1555-62. doi: 10.1016/j.bbabio.2010.05.007. Epub 2010 May 21. Biochim Biophys Acta. 2010. PMID: 20471951 Free PMC article.
Marine n3 polyunsaturated fatty acids enhance resistance to mitochondrial permeability transition in heart failure but do not improve survival.
Galvao TF, Khairallah RJ, Dabkowski ER, Brown BH, Hecker PA, O'Connell KA, O'Shea KM, Sabbah HN, Rastogi S, Daneault C, Des Rosiers C, Stanley WC. Galvao TF, et al. Among authors: hecker pa. Am J Physiol Heart Circ Physiol. 2013 Jan 1;304(1):H12-21. doi: 10.1152/ajpheart.00657.2012. Epub 2012 Oct 26. Am J Physiol Heart Circ Physiol. 2013. PMID: 23103493 Free PMC article.
Docosahexaenoic acid supplementation alters key properties of cardiac mitochondria and modestly attenuates development of left ventricular dysfunction in pressure overload-induced heart failure.
Dabkowski ER, O'Connell KA, Xu W, Ribeiro RF Jr, Hecker PA, Shekar KC, Daneault C, Des Rosiers C, Stanley WC. Dabkowski ER, et al. Among authors: hecker pa. Cardiovasc Drugs Ther. 2013 Dec;27(6):499-510. doi: 10.1007/s10557-013-6487-4. Cardiovasc Drugs Ther. 2013. PMID: 24013804 Free PMC article.
Dietary omega-3 fatty acids alter cardiac mitochondrial phospholipid composition and delay Ca2+-induced permeability transition.
O'Shea KM, Khairallah RJ, Sparagna GC, Xu W, Hecker PA, Robillard-Frayne I, Des Rosiers C, Kristian T, Murphy RC, Fiskum G, Stanley WC. O'Shea KM, et al. Among authors: hecker pa. J Mol Cell Cardiol. 2009 Dec;47(6):819-27. doi: 10.1016/j.yjmcc.2009.08.014. Epub 2009 Aug 22. J Mol Cell Cardiol. 2009. PMID: 19703463 Free PMC article.
23 results