Heck AJR - Search Results

1

Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1.

Harding RJ, Deme JC, Hevler JF, Tamara S, Lemak A, Cantle JP, Szewczyk MM, Begeja N, Goss S, Zuo X, Loppnau P, Seitova A, Hutchinson A, Fan L, Truant R, Schapira M, Carroll JB, Heck AJR, Lea SM, Arrowsmith CH. Harding RJ, et al. Among authors: heck ajr. Commun Biol. 2021 Dec 8;4(1):1374. doi: 10.1038/s42003-021-02895-4. Commun Biol. 2021. PMID: 34880419 Free PMC article.

2

Structure and assembly of scalable porous protein cages.

Sasaki E, Böhringer D, van de Waterbeemd M, Leibundgut M, Zschoche R, Heck AJ, Ban N, Hilvert D. Sasaki E, et al. Nat Commun. 2017 Mar 10;8:14663. doi: 10.1038/ncomms14663. Nat Commun. 2017. PMID: 28281548 Free PMC article.

3

Phosphate Transfer in Activated Protein Complexes Reveals Interaction Sites.

Tamara S, Scheltema RA, Heck AJR, Leney AC. Tamara S, et al. Among authors: heck ajr. Angew Chem Int Ed Engl. 2017 Oct 23;56(44):13641-13644. doi: 10.1002/anie.201706749. Epub 2017 Sep 27. Angew Chem Int Ed Engl. 2017. PMID: 28869719

4

Distinct Stabilities of the Structurally Homologous Heptameric Co-Chaperonins GroES and gp31.

Dyachenko A, Tamara S, Heck AJR. Dyachenko A, et al. Among authors: heck ajr. J Am Soc Mass Spectrom. 2019 Jan;30(1):7-15. doi: 10.1007/s13361-018-1910-5. Epub 2018 May 7. J Am Soc Mass Spectrom. 2019. PMID: 29736602 Free PMC article.

5

Dissecting ribosomal particles throughout the kingdoms of life using advanced hybrid mass spectrometry methods.

van de Waterbeemd M, Tamara S, Fort KL, Damoc E, Franc V, Bieri P, Itten M, Makarov A, Ban N, Heck AJR. van de Waterbeemd M, et al. Among authors: heck ajr. Nat Commun. 2018 Jun 27;9(1):2493. doi: 10.1038/s41467-018-04853-x. Nat Commun. 2018. PMID: 29950687 Free PMC article.

6

Expanding the mass range for UVPD-based native top-down mass spectrometry.

Greisch JF, Tamara S, Scheltema RA, Maxwell HWR, Fagerlund RD, Fineran PC, Tetter S, Hilvert D, Heck AJR. Greisch JF, et al. Among authors: heck ajr. Chem Sci. 2019 Jul 1;10(30):7163-7171. doi: 10.1039/c9sc01857c. eCollection 2019 Aug 14. Chem Sci. 2019. PMID: 31588283 Free PMC article.

7

A wealth of genotype-specific proteoforms fine-tunes hemoglobin scavenging by haptoglobin.

Tamara S, Franc V, Heck AJR. Tamara S, et al. Among authors: heck ajr. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15554-15564. doi: 10.1073/pnas.2002483117. Epub 2020 Jun 19. Proc Natl Acad Sci U S A. 2020. PMID: 32561649 Free PMC article.

8

Selective cross-linking of coinciding protein assemblies by in-gel cross-linking mass spectrometry.

Hevler JF, Lukassen MV, Cabrera-Orefice A, Arnold S, Pronker MF, Franc V, Heck AJR. Hevler JF, et al. Among authors: heck ajr. EMBO J. 2021 Feb 15;40(4):e106174. doi: 10.15252/embj.2020106174. Epub 2021 Jan 18. EMBO J. 2021. PMID: 33459420 Free PMC article.

9

Selectivity over coverage in de novo sequencing of IgGs.

den Boer MA, Greisch JF, Tamara S, Bondt A, Heck AJR. den Boer MA, et al. Among authors: heck ajr. Chem Sci. 2020 Oct 6;11(43):11886-11896. doi: 10.1039/d0sc03438j. eCollection 2020 Nov 21. Chem Sci. 2020. PMID: 33520151 Free PMC article.

10

Generating Informative Sequence Tags from Antigen-Binding Regions of Heavily Glycosylated IgA1 Antibodies by Native Top-Down Electron Capture Dissociation.

Greisch JF, den Boer MA, Beurskens F, Schuurman J, Tamara S, Bondt A, Heck AJR. Greisch JF, et al. Among authors: heck ajr. J Am Soc Mass Spectrom. 2021 Jun 2;32(6):1326-1335. doi: 10.1021/jasms.0c00461. Epub 2021 Feb 11. J Am Soc Mass Spectrom. 2021. PMID: 33570406 Free PMC article.

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