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Antibody-drug conjugate payloads.
Anderl J, Faulstich H, Hechler T, Kulke M. Anderl J, et al. Among authors: hechler t. Methods Mol Biol. 2013;1045:51-70. doi: 10.1007/978-1-62703-541-5_4. Methods Mol Biol. 2013. PMID: 23913141 Review.
HDP-101, an Anti-BCMA Antibody-Drug Conjugate, Safely Delivers Amanitin to Induce Cell Death in Proliferating and Resting Multiple Myeloma Cells.
Figueroa-Vazquez V, Ko J, Breunig C, Baumann A, Giesen N, Pálfi A, Müller C, Lutz C, Hechler T, Kulke M, Müller-Tidow C, Krämer A, Goldschmidt H, Pahl A, Raab MS. Figueroa-Vazquez V, et al. Among authors: hechler t. Mol Cancer Ther. 2021 Feb;20(2):367-378. doi: 10.1158/1535-7163.MCT-20-0287. Epub 2020 Dec 9. Mol Cancer Ther. 2021. PMID: 33298585
AGR2-Dependent Nuclear Import of RNA Polymerase II Constitutes a Specific Target of Pancreatic Ductal Adenocarcinoma in the Context of Wild-Type p53.
Zhang Z, Li H, Deng Y, Schuck K, Raulefs S, Maeritz N, Yu Y, Hechler T, Pahl A, Fernández-Sáiz V, Wan Y, Wang G, Engleitner T, Öllinger R, Rad R, Reichert M, Diakopoulos KN, Weber V, Li J, Shen S, Zou X, Kleeff J, Mihaljevic A, Michalski CW, Algül H, Friess H, Kong B. Zhang Z, et al. Among authors: hechler t. Gastroenterology. 2021 Nov;161(5):1601-1614.e23. doi: 10.1053/j.gastro.2021.07.030. Epub 2021 Jul 23. Gastroenterology. 2021. PMID: 34303658
Targeted immunotherapy for HER2-low breast cancer with 17p loss.
Li Y, Sun Y, Kulke M, Hechler T, Van der Jeught K, Dong T, He B, Miller KD, Radovich M, Schneider BP, Pahl A, Zhang X, Lu X. Li Y, et al. Among authors: hechler t. Sci Transl Med. 2021 Feb 10;13(580):eabc6894. doi: 10.1126/scitranslmed.abc6894. Sci Transl Med. 2021. PMID: 33568521 Free PMC article.
78 results