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Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis.
Raselli T, Hearn T, Wyss A, Atrott K, Peter A, Frey-Wagner I, Spalinger MR, Maggio EM, Sailer AW, Schmitt J, Schreiner P, Moncsek A, Mertens J, Scharl M, Griffiths WJ, Bueter M, Geier A, Rogler G, Wang Y, Misselwitz B. Raselli T, et al. Among authors: hearn t. J Lipid Res. 2019 Jul;60(7):1270-1283. doi: 10.1194/jlr.M093229. Epub 2019 May 21. J Lipid Res. 2019. PMID: 31113816 Free PMC article.
Current trends in oxysterol research.
Griffiths WJ, Abdel-Khalik J, Hearn T, Yutuc E, Morgan AH, Wang Y. Griffiths WJ, et al. Among authors: hearn t. Biochem Soc Trans. 2016 Apr 15;44(2):652-8. doi: 10.1042/BST20150255. Biochem Soc Trans. 2016. PMID: 27068984 Free PMC article. Review.
Identification of unusual oxysterols and bile acids with 7-oxo or 3β,5α,6β-trihydroxy functions in human plasma by charge-tagging mass spectrometry with multistage fragmentation.
Griffiths WJ, Gilmore I, Yutuc E, Abdel-Khalik J, Crick PJ, Hearn T, Dickson A, Bigger BW, Wu TH, Goenka A, Ghosh A, Jones SA, Wang Y. Griffiths WJ, et al. Among authors: hearn t. J Lipid Res. 2018 Jun;59(6):1058-1070. doi: 10.1194/jlr.D083246. Epub 2018 Apr 6. J Lipid Res. 2018. PMID: 29626102 Free PMC article.
Cholesterolomics: An update.
Griffiths WJ, Abdel-Khalik J, Yutuc E, Morgan AH, Gilmore I, Hearn T, Wang Y. Griffiths WJ, et al. Among authors: hearn t. Anal Biochem. 2017 May 1;524:56-67. doi: 10.1016/j.ab.2017.01.009. Epub 2017 Jan 10. Anal Biochem. 2017. PMID: 28087213 Free PMC article. Review.
Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders.
Griffiths WJ, Yutuc E, Abdel-Khalik J, Crick PJ, Hearn T, Dickson A, Bigger BW, Hoi-Yee Wu T, Goenka A, Ghosh A, Jones SA, Covey DF, Ory DS, Wang Y. Griffiths WJ, et al. Among authors: hearn t. Free Radic Biol Med. 2019 Nov 20;144:124-133. doi: 10.1016/j.freeradbiomed.2019.04.020. Epub 2019 Apr 19. Free Radic Biol Med. 2019. PMID: 31009661 Free PMC article.
Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates.
Abdel-Khalik J, Hearn T, Dickson AL, Crick PJ, Yutuc E, Austin-Muttitt K, Bigger BW, Morris AA, Shackleton CH, Clayton PT, Iida T, Sircar R, Rohatgi R, Marschall HU, Sjövall J, Björkhem I, Mullins JGL, Griffiths WJ, Wang Y. Abdel-Khalik J, et al. Among authors: hearn t. J Steroid Biochem Mol Biol. 2021 Feb;206:105794. doi: 10.1016/j.jsbmb.2020.105794. Epub 2020 Nov 24. J Steroid Biochem Mol Biol. 2021. PMID: 33246156 Free PMC article.
155 results