Heap JT - Search Results

1

ClosTron-mediated engineering of Clostridium.

Kuehne SA, Heap JT, Cooksley CM, Cartman ST, Minton NP. Kuehne SA, et al. Among authors: heap jt. Methods Mol Biol. 2011;765:389-407. doi: 10.1007/978-1-61779-197-0_23. Methods Mol Biol. 2011. PMID: 21815105

2

Binding of the anticancer prodrug CB1954 to the activating enzyme NQO2 revealed by the crystal structure of their complex.

AbuKhader M, Heap J, De Matteis C, Kellam B, Doughty SW, Minton N, Paoli M. AbuKhader M, et al. J Med Chem. 2005 Dec 1;48(24):7714-9. doi: 10.1021/jm050730n. J Med Chem. 2005. PMID: 16302811

3

The ClosTron: a universal gene knock-out system for the genus Clostridium.

Heap JT, Pennington OJ, Cartman ST, Carter GP, Minton NP. Heap JT, et al. J Microbiol Methods. 2007 Sep;70(3):452-64. doi: 10.1016/j.mimet.2007.05.021. Epub 2007 Jun 18. J Microbiol Methods. 2007. PMID: 17658189

4

Crystallization and preliminary X-ray characterization of the Bacillus amyloliquefaciens YwrO enzyme.

AbuKhader MM, Heap J, De Matteis CI, Doughty SW, Minton N, Paoli M. AbuKhader MM, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Sep 1;63(Pt 9):746-50. doi: 10.1107/S1744309107035816. Epub 2007 Aug 10. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17768344 Free PMC article.

5

A modular system for Clostridium shuttle plasmids.

Heap JT, Pennington OJ, Cartman ST, Minton NP. Heap JT, et al. J Microbiol Methods. 2009 Jul;78(1):79-85. doi: 10.1016/j.mimet.2009.05.004. Epub 2009 May 13. J Microbiol Methods. 2009. PMID: 19445976

6

The ClosTron: Mutagenesis in Clostridium refined and streamlined.

Heap JT, Kuehne SA, Ehsaan M, Cartman ST, Cooksley CM, Scott JC, Minton NP. Heap JT, et al. J Microbiol Methods. 2010 Jan;80(1):49-55. doi: 10.1016/j.mimet.2009.10.018. Epub 2009 Nov 3. J Microbiol Methods. 2010. PMID: 19891996

7

Construction of a nontoxigenic Clostridium botulinum strain for food challenge studies.

Bradshaw M, Marshall KM, Heap JT, Tepp WH, Minton NP, Johnson EA. Bradshaw M, et al. Among authors: heap jt. Appl Environ Microbiol. 2010 Jan;76(2):387-93. doi: 10.1128/AEM.02005-09. Epub 2009 Nov 20. Appl Environ Microbiol. 2010. PMID: 19933346 Free PMC article.

8

SleC is essential for germination of Clostridium difficile spores in nutrient-rich medium supplemented with the bile salt taurocholate.

Burns DA, Heap JT, Minton NP. Burns DA, et al. Among authors: heap jt. J Bacteriol. 2010 Feb;192(3):657-64. doi: 10.1128/JB.01209-09. Epub 2009 Nov 20. J Bacteriol. 2010. PMID: 19933358 Free PMC article.

9

The emergence of 'hypervirulence' in Clostridium difficile.

Cartman ST, Heap JT, Kuehne SA, Cockayne A, Minton NP. Cartman ST, et al. Among authors: heap jt. Int J Med Microbiol. 2010 Aug;300(6):387-95. doi: 10.1016/j.ijmm.2010.04.008. Epub 2010 May 23. Int J Med Microbiol. 2010. PMID: 20547099 Review.

10

ClosTron-targeted mutagenesis.

Heap JT, Cartman ST, Kuehne SA, Cooksley C, Minton NP. Heap JT, et al. Methods Mol Biol. 2010;646:165-82. doi: 10.1007/978-1-60327-365-7_11. Methods Mol Biol. 2010. PMID: 20597009

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