He S - Search Results

1

Rational Design of Multitarget-Directed Ligands: Strategies and Emerging Paradigms.

Zhou J, Jiang X, He S, Jiang H, Feng F, Liu W, Qu W, Sun H. Zhou J, et al. Among authors: he s. J Med Chem. 2019 Oct 24;62(20):8881-8914. doi: 10.1021/acs.jmedchem.9b00017. Epub 2019 May 28. J Med Chem. 2019. PMID: 31082225 Review.

2

Long-term Stress with Hyperglucocorticoidemia-induced Hepatic Steatosis with VLDL Overproduction Is Dependent on both 5-HT2 Receptor and 5-HT Synthesis in Liver.

Fu J, Ma S, Li X, An S, Li T, Guo K, Lin M, Qu W, Wang S, Dong X, Han X, Fu T, Huang X, Wang T, He S. Fu J, et al. Among authors: he s. Int J Biol Sci. 2016 Jan 1;12(2):219-34. doi: 10.7150/ijbs.13062. eCollection 2016. Int J Biol Sci. 2016. PMID: 26884719 Free PMC article.

3

Gamma secretase inhibitors: a patent review (2013 - 2015).

Gu K, Li Q, Lin H, Zhu J, Mo J, He S, Lu X, Jiang X, Sun H. Gu K, et al. Among authors: he s. Expert Opin Ther Pat. 2017 Jul;27(7):851-866. doi: 10.1080/13543776.2017.1313231. Epub 2017 Apr 10. Expert Opin Ther Pat. 2017. PMID: 28350212 Review.

4

Design of Small Molecule Autophagy Modulators: A Promising Druggable Strategy.

He S, Li Q, Jiang X, Lu X, Feng F, Qu W, Chen Y, Sun H. He S, et al. J Med Chem. 2018 Jun 14;61(11):4656-4687. doi: 10.1021/acs.jmedchem.7b01019. Epub 2017 Dec 20. J Med Chem. 2018. PMID: 29211480 Review.

5

Investigation of multi-target-directed ligands (MTDLs) with butyrylcholinesterase (BuChE) and indoleamine 2,3-dioxygenase 1 (IDO1) inhibition: The design, synthesis of miconazole analogues targeting Alzheimer's disease.

Lu X, He SY, Li Q, Yang H, Jiang X, Lin H, Chen Y, Qu W, Feng F, Bian Y, Zhou Y, Sun H. Lu X, et al. Bioorg Med Chem. 2018 May 1;26(8):1665-1674. doi: 10.1016/j.bmc.2018.02.014. Epub 2018 Feb 13. Bioorg Med Chem. 2018. PMID: 29475581

6

Dual GSK-3β/AChE Inhibitors as a New Strategy for Multitargeting Anti-Alzheimer's Disease Drug Discovery.

Jiang XY, Chen TK, Zhou JT, He SY, Yang HY, Chen Y, Qu W, Feng F, Sun HP. Jiang XY, et al. ACS Med Chem Lett. 2018 Feb 9;9(3):171-176. doi: 10.1021/acsmedchemlett.7b00463. eCollection 2018 Mar 8. ACS Med Chem Lett. 2018. PMID: 29541355 Free PMC article.

7

The Development of Pharmacophore Modeling: Generation and Recent Applications in Drug Discovery.

Lu X, Yang H, Chen Y, Li Q, He SY, Jiang X, Feng F, Qu W, Sun H. Lu X, et al. Curr Pharm Des. 2018;24(29):3424-3439. doi: 10.2174/1381612824666180810162944. Curr Pharm Des. 2018. PMID: 30101699 Review.

8

Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease.

Li Q, He S, Chen Y, Feng F, Qu W, Sun H. Li Q, et al. Among authors: he s. Eur J Med Chem. 2018 Oct 5;158:463-477. doi: 10.1016/j.ejmech.2018.09.031. Epub 2018 Sep 13. Eur J Med Chem. 2018. PMID: 30243151 Review.

9

Reasonably activating Nrf2: A long-term, effective and controllable strategy for neurodegenerative diseases.

Li Q, Xing S, Chen Y, Liao Q, Li Q, Liu Y, He S, Feng F, Chen Y, Zhang J, Liu W, Guo Q, Sun Y, Sun H. Li Q, et al. Among authors: he s. Eur J Med Chem. 2020 Jan 1;185:111862. doi: 10.1016/j.ejmech.2019.111862. Epub 2019 Nov 8. Eur J Med Chem. 2020. PMID: 31735576 Review.

10

Overview of AKR1C3: Inhibitor Achievements and Disease Insights.

Liu Y, He S, Chen Y, Liu Y, Feng F, Liu W, Guo Q, Zhao L, Sun H. Liu Y, et al. Among authors: he s. J Med Chem. 2020 Oct 22;63(20):11305-11329. doi: 10.1021/acs.jmedchem.9b02138. Epub 2020 Jun 10. J Med Chem. 2020. PMID: 32463235 Review.

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