He L - Search Results

1

A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development.

Modzelewski AJ, Shao W, Chen J, Lee A, Qi X, Noon M, Tjokro K, Sales G, Biton A, Anand A, Speed TP, Xuan Z, Wang T, Risso D, He L. Modzelewski AJ, et al. Among authors: he l. Cell. 2021 Oct 28;184(22):5541-5558.e22. doi: 10.1016/j.cell.2021.09.021. Epub 2021 Oct 12. Cell. 2021. PMID: 34644528 Free PMC article.

2

Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells.

Choi YJ, Lin CP, Risso D, Chen S, Kim TA, Tan MH, Li JB, Wu Y, Chen C, Xuan Z, Macfarlan T, Peng W, Lloyd KC, Kim SY, Speed TP, He L. Choi YJ, et al. Among authors: he l. Science. 2017 Feb 10;355(6325):eaag1927. doi: 10.1126/science.aag1927. Epub 2017 Jan 12. Science. 2017. PMID: 28082412 Free PMC article.

3

Mammalian genome innovation through transposon domestication.

Modzelewski AJ, Gan Chong J, Wang T, He L. Modzelewski AJ, et al. Among authors: he l. Nat Cell Biol. 2022 Sep;24(9):1332-1340. doi: 10.1038/s41556-022-00970-4. Epub 2022 Aug 25. Nat Cell Biol. 2022. PMID: 36008480 Free PMC article. Review.

4

Klf5 establishes bi-potential cell fate by dual regulation of ICM and TE specification genes.

Kinisu M, Choi YJ, Cattoglio C, Liu K, Roux de Bezieux H, Valbuena R, Pum N, Dudoit S, Huang H, Xuan Z, Kim SY, He L. Kinisu M, et al. Among authors: he l. Cell Rep. 2021 Nov 9;37(6):109982. doi: 10.1016/j.celrep.2021.109982. Cell Rep. 2021. PMID: 34758315 Free PMC article.

5

Highly Efficient Mouse Genome Editing by CRISPR Ribonucleoprotein Electroporation of Zygotes.

Chen S, Lee B, Lee AY, Modzelewski AJ, He L. Chen S, et al. Among authors: he l. J Biol Chem. 2016 Jul 8;291(28):14457-67. doi: 10.1074/jbc.M116.733154. Epub 2016 May 5. J Biol Chem. 2016. PMID: 27151215 Free PMC article.

6

Multimodal detection of protein isoforms and nucleic acids from mouse pre-implantation embryos.

Rosàs-Canyelles E, Modzelewski AJ, Geldert A, He L, Herr AE. Rosàs-Canyelles E, et al. Among authors: he l. Nat Protoc. 2021 Feb;16(2):1062-1088. doi: 10.1038/s41596-020-00449-2. Epub 2021 Jan 15. Nat Protoc. 2021. PMID: 33452502 Free PMC article.

7

Assessing heterogeneity among single embryos and single blastomeres using open microfluidic design.

Rosàs-Canyelles E, Modzelewski AJ, Geldert A, He L, Herr AE. Rosàs-Canyelles E, et al. Among authors: he l. Sci Adv. 2020 Apr 22;6(17):eaay1751. doi: 10.1126/sciadv.aay1751. eCollection 2020 Apr. Sci Adv. 2020. PMID: 32494630 Free PMC article.

8

Efficient mouse genome engineering by CRISPR-EZ technology.

Modzelewski AJ, Chen S, Willis BJ, Lloyd KCK, Wood JA, He L. Modzelewski AJ, et al. Among authors: he l. Nat Protoc. 2018 Jun;13(6):1253-1274. doi: 10.1038/nprot.2018.012. Epub 2018 May 10. Nat Protoc. 2018. PMID: 29748649 Free PMC article.

9

A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.

Okada N, Lin CP, Ribeiro MC, Biton A, Lai G, He X, Bu P, Vogel H, Jablons DM, Keller AC, Wilkinson JE, He B, Speed TP, He L. Okada N, et al. Among authors: he x, he l, he b. Genes Dev. 2014 Mar 1;28(5):438-50. doi: 10.1101/gad.233585.113. Epub 2014 Feb 14. Genes Dev. 2014. PMID: 24532687 Free PMC article.

10

Multimodal detection of protein isoforms and nucleic acids from low starting cell numbers.

Rosàs-Canyelles E, Modzelewski AJ, Gomez Martinez AE, Geldert A, Gopal A, He L, Herr AE. Rosàs-Canyelles E, et al. Among authors: he l. Lab Chip. 2021 Jun 15;21(12):2427-2436. doi: 10.1039/d1lc00073j. Lab Chip. 2021. PMID: 33978041 Free PMC article.

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