He L - Search Results

1

He L. He L. Trends Pharmacol Sci. 2020 Nov;41(11):868-881. doi: 10.1016/j.tips.2020.09.001. Epub 2020 Sep 28. Trends Pharmacol Sci. 2020. PMID: 32994049 Free PMC article. Review.

2

Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein.

He L, Sabet A, Djedjos S, Miller R, Sun X, Hussain MA, Radovick S, Wondisford FE. He L, et al. Cell. 2009 May 15;137(4):635-46. doi: 10.1016/j.cell.2009.03.016. Cell. 2009. PMID: 19450513 Free PMC article.

3

Potential biomarker of metformin action.

He L, Meng S, Germain-Lee EL, Radovick S, Wondisford FE. He L, et al. J Endocrinol. 2014 Jun;221(3):363-9. doi: 10.1530/JOE-14-0084. Epub 2014 Mar 17. J Endocrinol. 2014. PMID: 24639469 Free PMC article.

4

Metformin activates AMP-activated protein kinase by promoting formation of the αβγ heterotrimeric complex.

Meng S, Cao J, He Q, Xiong L, Chang E, Radovick S, Wondisford FE, He L. Meng S, et al. Among authors: he l, he q. J Biol Chem. 2015 Feb 6;290(6):3793-802. doi: 10.1074/jbc.M114.604421. Epub 2014 Dec 23. J Biol Chem. 2015. PMID: 25538235 Free PMC article.

5

Metformin action: concentrations matter.

He L, Wondisford FE. He L, et al. Cell Metab. 2015 Feb 3;21(2):159-162. doi: 10.1016/j.cmet.2015.01.003. Cell Metab. 2015. PMID: 25651170 Free article.

6

Current understanding of metformin effect on the control of hyperglycemia in diabetes.

An H, He L. An H, et al. Among authors: he l. J Endocrinol. 2016 Mar;228(3):R97-106. doi: 10.1530/JOE-15-0447. Epub 2016 Jan 7. J Endocrinol. 2016. PMID: 26743209 Free PMC article. Review.

7

Activation of the cAMP-PKA pathway Antagonizes Metformin Suppression of Hepatic Glucose Production.

He L, Chang E, Peng J, An H, McMillin SM, Radovick S, Stratakis CA, Wondisford FE. He L, et al. J Biol Chem. 2016 May 13;291(20):10562-70. doi: 10.1074/jbc.M116.719666. Epub 2016 Mar 21. J Biol Chem. 2016. PMID: 27002150 Free PMC article.

8

Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK.

Wang Y, An H, Liu T, Qin C, Sesaki H, Guo S, Radovick S, Hussain M, Maheshwari A, Wondisford FE, O'Rourke B, He L. Wang Y, et al. Among authors: he l. Cell Rep. 2019 Nov 5;29(6):1511-1523.e5. doi: 10.1016/j.celrep.2019.09.070. Cell Rep. 2019. PMID: 31693892 Free PMC article.

9

Dysregulated expression of monoacylglycerol lipase is a marker for anti-diabetic drug metformin-targeted therapy to correct impaired neurogenesis and spatial memory in Alzheimer's disease.

Syal C, Kosaraju J, Hamilton L, Aumont A, Chu A, Sarma SN, Thomas J, Seegobin M, Dilworth FJ, He L, Wondisford FE, Zimmermann R, Parent M, Fernandes K, Wang J. Syal C, et al. Among authors: he l. Theranostics. 2020 May 15;10(14):6337-6360. doi: 10.7150/thno.44962. eCollection 2020. Theranostics. 2020. PMID: 32483456 Free PMC article.

10

The importance of the AMPK gamma 1 subunit in metformin suppression of liver glucose production.

An H, Wang Y, Qin C, Li M, Maheshwari A, He L. An H, et al. Among authors: he l. Sci Rep. 2020 Jun 26;10(1):10482. doi: 10.1038/s41598-020-67030-5. Sci Rep. 2020. PMID: 32591547 Free PMC article.

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