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Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike.
Qu K, Chen Q, Ciazynska KA, Liu B, Zhang X, Wang J, He Y, Guan J, He J, Liu T, Zhang X, Carter AP, Xiong X, Briggs JAG. Qu K, et al. Among authors: he y, he j. PLoS Pathog. 2022 Jul 29;18(7):e1010583. doi: 10.1371/journal.ppat.1010583. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35905112 Free PMC article.
Novel Monoclonal Antibodies and Recombined Antibodies Against Variant SARS-CoV-2.
Xie J, Ding C, He J, Zhang Y, Ni S, Zhang X, Chen Q, Wang J, Huang L, He H, Li W, Ma H, Jin T, Zhang S, Gao Y. Xie J, et al. Among authors: he h, he j. Front Immunol. 2021 Aug 30;12:715464. doi: 10.3389/fimmu.2021.715464. eCollection 2021. Front Immunol. 2021. PMID: 34539645 Free PMC article.
A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD.
Wang X, Hu A, Chen X, Zhang Y, Yu F, Yue S, Li A, Zhang J, Pan Z, Yang Y, Lin Y, Gao L, Zhou J, Zhao J, Li F, Shi Y, Huang F, Yang X, Peng Y, Tu L, Zhang H, Zheng H, He J, Zhang H, Xu L, Huang Q, Zhu Y, Deng K, Ye L. Wang X, et al. Among authors: he j. Signal Transduct Target Ther. 2022 Apr 5;7(1):114. doi: 10.1038/s41392-022-00954-8. Signal Transduct Target Ther. 2022. PMID: 35383141 Free PMC article.
SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope.
He P, Liu B, Gao X, Yan Q, Pei R, Sun J, Chen Q, Hou R, Li Z, Zhang Y, Zhao J, Sun H, Feng B, Wang Q, Yi H, Hu P, Li P, Zhang Y, Chen Z, Niu X, Zhong X, Jin L, Liu X, Qu K, Ciazynska KA, Carter AP, Briggs JAG, Chen J, Liu J, Chen X, He J, Chen L, Xiong X. He P, et al. Among authors: he j. Nat Microbiol. 2022 Oct;7(10):1635-1649. doi: 10.1038/s41564-022-01235-4. Epub 2022 Sep 23. Nat Microbiol. 2022. PMID: 36151403 Free PMC article.
Somatically hypermutated antibodies isolated from SARS-CoV-2 Delta infected patients cross-neutralize heterologous variants.
Yu H, Liu B, Zhang Y, Gao X, Wang Q, Xiang H, Peng X, Xie C, Wang Y, Hu P, Shi J, Shi Q, Zheng P, Feng C, Tang G, Liu X, Guo L, Lin X, Li J, Liu C, Huang Y, Yang N, Chen Q, Li Z, Su M, Yan Q, Pei R, Chen X, Liu L, Hu F, Liang D, Ke B, Ke C, Li F, He J, Wang M, Chen L, Xiong X, Tang X. Yu H, et al. Among authors: he j. Nat Commun. 2023 Feb 24;14(1):1058. doi: 10.1038/s41467-023-36761-0. Nat Commun. 2023. PMID: 36828833 Free PMC article.
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