He HH - Search Results

1

LSD1 Inhibition Disrupts Super-Enhancer-Driven Oncogenic Transcriptional Programs in Castration-Resistant Prostate Cancer.

Li M, Liu M, Han W, Wang Z, Han D, Patalano S, Macoska JA, Balk SP, He HH, Corey E, Gao S, Cai C. Li M, et al. Among authors: he hh. Cancer Res. 2023 May 15;83(10):1684-1698. doi: 10.1158/0008-5472.CAN-22-2433. Cancer Res. 2023. PMID: 36877164 Free PMC article.

2

Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1.

Cai C, He HH, Chen S, Coleman I, Wang H, Fang Z, Chen S, Nelson PS, Liu XS, Brown M, Balk SP. Cai C, et al. Among authors: he hh. Cancer Cell. 2011 Oct 18;20(4):457-71. doi: 10.1016/j.ccr.2011.09.001. Cancer Cell. 2011. PMID: 22014572 Free PMC article.

3

EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent.

Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis RT, Wu X, Stack EC, Loda M, Liu T, Xu H, Cato L, Thornton JE, Gregory RI, Morrissey C, Vessella RL, Montironi R, Magi-Galluzzi C, Kantoff PW, Balk SP, Liu XS, Brown M. Xu K, et al. Among authors: he hh. Science. 2012 Dec 14;338(6113):1465-9. doi: 10.1126/science.1227604. Science. 2012. PMID: 23239736 Free PMC article.

4

ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer.

Cai C, Wang H, He HH, Chen S, He L, Ma F, Mucci L, Wang Q, Fiore C, Sowalsky AG, Loda M, Liu XS, Brown M, Balk SP, Yuan X. Cai C, et al. Among authors: he hh, he l. J Clin Invest. 2013 Mar;123(3):1109-22. doi: 10.1172/JCI66666. Epub 2013 Feb 15. J Clin Invest. 2013. PMID: 23426182 Free PMC article.

5

MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A.

Sun T, Wang X, He HH, Sweeney CJ, Liu SX, Brown M, Balk S, Lee GS, Kantoff PW. Sun T, et al. Among authors: he hh. Oncogene. 2014 May 22;33(21):2790-800. doi: 10.1038/onc.2013.230. Epub 2013 Jun 17. Oncogene. 2014. PMID: 23770851 Free PMC article.

6

Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity.

Cai C, He HH, Gao S, Chen S, Yu Z, Gao Y, Chen S, Chen MW, Zhang J, Ahmed M, Wang Y, Metzger E, Schüle R, Liu XS, Brown M, Balk SP. Cai C, et al. Among authors: he hh. Cell Rep. 2014 Dec 11;9(5):1618-1627. doi: 10.1016/j.celrep.2014.11.008. Epub 2014 Dec 4. Cell Rep. 2014. PMID: 25482560 Free PMC article.

7

PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy.

Hsieh CL, Botta G, Gao S, Li T, Van Allen EM, Treacy DJ, Cai C, He HH, Sweeney CJ, Brown M, Balk SP, Nelson PS, Garraway LA, Kantoff PW. Hsieh CL, et al. Among authors: he hh. Cancer Res. 2015 May 15;75(10):1944-8. doi: 10.1158/0008-5472.CAN-14-3602. Epub 2015 Mar 25. Cancer Res. 2015. PMID: 25808865 Free PMC article.

8

SOX9 drives WNT pathway activation in prostate cancer.

Ma F, Ye H, He HH, Gerrin SJ, Chen S, Tanenbaum BA, Cai C, Sowalsky AG, He L, Wang H, Balk SP, Yuan X. Ma F, et al. Among authors: he hh, he l. J Clin Invest. 2016 May 2;126(5):1745-58. doi: 10.1172/JCI78815. Epub 2016 Apr 4. J Clin Invest. 2016. PMID: 27043282 Free PMC article.

9

Androgen Receptor Tumor Suppressor Function Is Mediated by Recruitment of Retinoblastoma Protein.

Gao S, Gao Y, He HH, Han D, Han W, Avery A, Macoska JA, Liu X, Chen S, Ma F, Chen S, Balk SP, Cai C. Gao S, et al. Among authors: he hh. Cell Rep. 2016 Oct 18;17(4):966-976. doi: 10.1016/j.celrep.2016.09.064. Cell Rep. 2016. PMID: 27760327 Free PMC article.

10

LSD1-Mediated Epigenetic Reprogramming Drives CENPE Expression and Prostate Cancer Progression.

Liang Y, Ahmed M, Guo H, Soares F, Hua JT, Gao S, Lu C, Poon C, Han W, Langstein J, Ekram MB, Li B, Davicioni E, Takhar M, Erho N, Karnes RJ, Chadwick D, van der Kwast T, Boutros PC, Arrowsmith CH, Feng FY, Joshua AM, Zoubeidi A, Cai C, He HH. Liang Y, et al. Among authors: he hh. Cancer Res. 2017 Oct 15;77(20):5479-5490. doi: 10.1158/0008-5472.CAN-17-0496. Epub 2017 Sep 15. Cancer Res. 2017. PMID: 28916652

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