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Design, synthesis, and biological evaluation of anti-EV71 agents.
Li P, Yang B, Hao F, Wang P, He H, Huang L, Zhang X, Zhang S, Peng X, Yin K, Hu J, Chen X, Gu Z, Wang L, Shen L, Hu G, Li N, Li J, Chen S, Xiao W, Wang Z, Guo Q, Chang X, Zhang L, Cai Q, Lin T. Li P, et al. Among authors: he h. Bioorg Med Chem Lett. 2016 Jul 15;26(14):3346-3350. doi: 10.1016/j.bmcl.2016.05.036. Epub 2016 May 14. Bioorg Med Chem Lett. 2016. PMID: 27234148
Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.
Ouyang X, Piatnitski EL, Pattaropong V, Chen X, He HY, Kiselyov AS, Velankar A, Kawakami J, Labelle M, Smith L 2nd, Lohman J, Lee SP, Malikzay A, Fleming J, Gerlak J, Wang Y, Rosler RL, Zhou K, Mitelman S, Camara M, Surguladze D, Doody JF, Tuma MC. Ouyang X, et al. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1191-6. doi: 10.1016/j.bmcl.2005.11.094. Epub 2006 Jan 11. Bioorg Med Chem Lett. 2006. PMID: 16377187
Michael acceptor in gambogic acid--Its role and application for potent antitumor agents.
Wang J, Shen W, Yuan Z, Lan L, Xu J, Wang C, Ma G, Shi W, Han L, Zhang Z, Hou L, Shen L, Jiang Z, He H, Xiao W, Wang Z, Guo Q, Li J, Chen S. Wang J, et al. Among authors: he h. Bioorg Med Chem Lett. 2015 Jul 15;25(14):2844-8. doi: 10.1016/j.bmcl.2015.04.100. Epub 2015 May 11. Bioorg Med Chem Lett. 2015. PMID: 26009165
Discovery of Potent EV71 Capsid Inhibitors for Treatment of HFMD.
Li P, Yu J, Hao F, He H, Shi X, Hu J, Wang L, Du C, Zhang X, Sun Y, Lin F, Gu Z, Xu D, Chen X, Shen L, Hu G, Li J, Chen S, Xiao W, Wang Z, Guo Q, Chang X, Tian X, Lin T. Li P, et al. Among authors: he h. ACS Med Chem Lett. 2017 Jul 10;8(8):841-846. doi: 10.1021/acsmedchemlett.7b00188. eCollection 2017 Aug 10. ACS Med Chem Lett. 2017. PMID: 28835799 Free PMC article.
Design, Synthesis, and Evaluation of Tetrahydropyrrolo[1,2-c]pyrimidines as Capsid Assembly Inhibitors for HBV Treatment.
Li X, Zhou K, He H, Zhou Q, Sun Y, Hou L, Shen L, Wang X, Zhou Y, Gong Z, He S, Jin H, Gu Z, Zhao S, Zhang L, Sun C, Zheng S, Cheng Z, Zhu Y, Zhang M, Li J, Chen S. Li X, et al. Among authors: he s, he h. ACS Med Chem Lett. 2017 Aug 24;8(9):969-974. doi: 10.1021/acsmedchemlett.7b00288. eCollection 2017 Sep 14. ACS Med Chem Lett. 2017. PMID: 28947946 Free PMC article.
Synthesis and Biological Evaluation of a Series of Bile Acid Derivatives as FXR Agonists for Treatment of NASH.
Xiao H, Li P, Li X, He H, Wang J, Guo F, Zhang J, Wei L, Zhang H, Shi Y, Hou L, Shen L, Chen Z, Du C, Fu S, Zhang P, Hao F, Wang P, Xu D, Liang W, Tian X, Zhang A, Cheng X, Yang L, Wang X, Zhang X, Li J, Chen S. Xiao H, et al. Among authors: he h. ACS Med Chem Lett. 2017 Oct 31;8(12):1246-1251. doi: 10.1021/acsmedchemlett.7b00318. eCollection 2017 Dec 14. ACS Med Chem Lett. 2017. PMID: 29259742 Free PMC article.
Structure-activity relationship study of a series of caspase inhibitors containing γ-amino acid moiety for treatment of cholestatic liver disease.
Mou J, Wu S, Luo Z, Guo F, He H, Wang J, Lin F, Guo F, Sun J, Shen L, Zeng M, Wang C, Xu D, Gu Z, Tian X, Zhang A, Xu H, Yang L, Zhang X, Li J, Chen S. Mou J, et al. Among authors: he h. Bioorg Med Chem Lett. 2018 Jun 1;28(10):1874-1878. doi: 10.1016/j.bmcl.2018.04.002. Epub 2018 Apr 4. Bioorg Med Chem Lett. 2018. PMID: 29650287
Correction to "The Discovery of 3,3'-Spiro[azetidine]-2-oxo-indoline Derivatives as Fusion Inhibitors for Treatment of RSV Infection".
Shi W, Jiang Z, He H, Xiao F, Lin F, Sun Y, Hou L, Shen L, Han L, Zeng M, Lai K, Gu Z, Chen X, Zhao T, Guo L, Yang C, Li J, Chen S. Shi W, et al. Among authors: he h. ACS Med Chem Lett. 2018 Mar 30;9(4):397. doi: 10.1021/acsmedchemlett.8b00139. eCollection 2018 Apr 12. ACS Med Chem Lett. 2018. PMID: 29671838 Free PMC article.
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