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Combining structure-based pharmacophore modeling, virtual screening, and in silico ADMET analysis to discover novel tetrahydro-quinoline based pyruvate kinase isozyme M2 activators with antitumor activity.
Chen C, Wang T, Wu F, Huang W, He G, Ouyang L, Xiang M, Peng C, Jiang Q. Chen C, et al. Among authors: he g. Drug Des Devel Ther. 2014 Sep 2;8:1195-210. doi: 10.2147/DDDT.S62921. eCollection 2014. Drug Des Devel Ther. 2014. PMID: 25214764 Free PMC article.
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