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Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.
Zhu W, Gregory JC, Org E, Buffa JA, Gupta N, Wang Z, Li L, Fu X, Wu Y, Mehrabian M, Sartor RB, McIntyre TM, Silverstein RL, Tang WHW, DiDonato JA, Brown JM, Lusis AJ, Hazen SL. Zhu W, et al. Among authors: hazen sl. Cell. 2016 Mar 24;165(1):111-124. doi: 10.1016/j.cell.2016.02.011. Epub 2016 Mar 10. Cell. 2016. PMID: 26972052 Free PMC article.
Increased atherosclerosis in myeloperoxidase-deficient mice.
Brennan ML, Anderson MM, Shih DM, Qu XD, Wang X, Mehta AC, Lim LL, Shi W, Hazen SL, Jacob JS, Crowley JR, Heinecke JW, Lusis AJ. Brennan ML, et al. Among authors: hazen sl. J Clin Invest. 2001 Feb;107(4):419-30. doi: 10.1172/JCI8797. J Clin Invest. 2001. PMID: 11181641 Free PMC article.
A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species.
Brennan ML, Wu W, Fu X, Shen Z, Song W, Frost H, Vadseth C, Narine L, Lenkiewicz E, Borchers MT, Lusis AJ, Lee JJ, Lee NA, Abu-Soud HM, Ischiropoulos H, Hazen SL. Brennan ML, et al. Among authors: hazen sl. J Biol Chem. 2002 May 17;277(20):17415-27. doi: 10.1074/jbc.M112400200. Epub 2002 Feb 27. J Biol Chem. 2002. PMID: 11877405 Free article.
A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.
Podrez EA, Poliakov E, Shen Z, Zhang R, Deng Y, Sun M, Finton PJ, Shan L, Febbraio M, Hajjar DP, Silverstein RL, Hoff HF, Salomon RG, Hazen SL. Podrez EA, et al. Among authors: hazen sl. J Biol Chem. 2002 Oct 11;277(41):38517-23. doi: 10.1074/jbc.M205924200. Epub 2002 Jul 26. J Biol Chem. 2002. PMID: 12145296 Free article.
Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions.
Sun M, Finnemann SC, Febbraio M, Shan L, Annangudi SP, Podrez EA, Hoppe G, Darrow R, Organisciak DT, Salomon RG, Silverstein RL, Hazen SL. Sun M, et al. Among authors: hazen sl. J Biol Chem. 2006 Feb 17;281(7):4222-30. doi: 10.1074/jbc.M509769200. Epub 2005 Dec 13. J Biol Chem. 2006. PMID: 16354659 Free PMC article.
521 results