Haynes AC - Search Results

1

Reduction of cysteine sulfinic acid in eukaryotic, typical 2-Cys peroxiredoxins by sulfiredoxin.

Lowther WT, Haynes AC. Lowther WT, et al. Among authors: haynes ac. Antioxid Redox Signal. 2011 Jul 1;15(1):99-109. doi: 10.1089/ars.2010.3564. Epub 2010 Dec 17. Antioxid Redox Signal. 2011. PMID: 20712415 Free PMC article. Review.

2

Molecular basis for the resistance of human mitochondrial 2-Cys peroxiredoxin 3 to hyperoxidation.

Haynes AC, Qian J, Reisz JA, Furdui CM, Lowther WT. Haynes AC, et al. J Biol Chem. 2013 Oct 11;288(41):29714-23. doi: 10.1074/jbc.M113.473470. Epub 2013 Sep 3. J Biol Chem. 2013. PMID: 24003226 Free PMC article.

3

Kinetic analysis of structural influences on the susceptibility of peroxiredoxins 2 and 3 to hyperoxidation.

Poynton RA, Peskin AV, Haynes AC, Lowther WT, Hampton MB, Winterbourn CC. Poynton RA, et al. Among authors: haynes ac. Biochem J. 2016 Feb 15;473(4):411-21. doi: 10.1042/BJ20150572. Epub 2015 Nov 27. Biochem J. 2016. PMID: 26614766 Free PMC article.

4

Novel hyperoxidation resistance motifs in 2-Cys peroxiredoxins.

Bolduc JA, Nelson KJ, Haynes AC, Lee J, Reisz JA, Graff AH, Clodfelter JE, Parsonage D, Poole LB, Furdui CM, Lowther WT. Bolduc JA, et al. Among authors: haynes ac. J Biol Chem. 2018 Jul 27;293(30):11901-11912. doi: 10.1074/jbc.RA117.001690. Epub 2018 Jun 8. J Biol Chem. 2018. PMID: 29884768 Free PMC article.

5

Disabling Mitochondrial Peroxide Metabolism via Combinatorial Targeting of Peroxiredoxin 3 as an Effective Therapeutic Approach for Malignant Mesothelioma.

Cunniff B, Newick K, Nelson KJ, Wozniak AN, Beuschel S, Leavitt B, Bhave A, Butnor K, Koenig A, Chouchani ET, James AM, Haynes AC, Lowther WT, Murphy MP, Shukla A, Heintz NH. Cunniff B, et al. Among authors: haynes ac. PLoS One. 2015 May 26;10(5):e0127310. doi: 10.1371/journal.pone.0127310. eCollection 2015. PLoS One. 2015. PMID: 26011724 Free PMC article.

6

Molecular basis of reduced pyridoxine 5'-phosphate oxidase catalytic activity in neonatal epileptic encephalopathy disorder.

Musayev FN, Di Salvo ML, Saavedra MA, Contestabile R, Ghatge MS, Haynes A, Schirch V, Safo MK. Musayev FN, et al. J Biol Chem. 2009 Nov 6;284(45):30949-56. doi: 10.1074/jbc.M109.038372. Epub 2009 Sep 15. J Biol Chem. 2009. PMID: 19759001 Free PMC article.

7

Evaluation of antihypertensive drugs in combination with enzyme replacement therapy in mice with Pompe disease.

Han SO, Haynes AC, Li S, Abraham DM, Kishnani PS, Steet R, Koeberl DD. Han SO, et al. Among authors: haynes ac. Mol Genet Metab. 2020 Feb;129(2):73-79. doi: 10.1016/j.ymgme.2019.10.005. Epub 2019 Oct 17. Mol Genet Metab. 2020. PMID: 31645300 Free PMC article.

8

A calming hug: Design and validation of a tactile aid to ease anxiety.

Haynes AC, Lywood A, Crowe EM, Fielding JL, Rossiter JM, Kent C. Haynes AC, et al. PLoS One. 2022 Mar 9;17(3):e0259838. doi: 10.1371/journal.pone.0259838. eCollection 2022. PLoS One. 2022. PMID: 35263344 Free PMC article.

9

Receptor-interacting protein 1 kinase inhibition therapeutically ameliorates experimental T cell-dependent colitis in mice.

Gobbetti T, Berger SB, Fountain K, Slocombe T, Rowles A, Pearse G, Harada I, Bertin J, Haynes AC, Beal AM. Gobbetti T, et al. Among authors: haynes ac. Cell Death Dis. 2020 Apr 6;11(4):220. doi: 10.1038/s41419-020-2423-2. Cell Death Dis. 2020. PMID: 32249785 Free PMC article. No abstract available.

10

Selective inhibition of BET proteins reduces pancreatic damage and systemic inflammation in bile acid- and fatty acid ethyl ester- but not caerulein-induced acute pancreatitis.

Huang W, Haynes AC, Mukherjee R, Wen L, Latawiec D, Tepikin AV, Criddle DN, Prinjha RK, Smithers N, Sutton R. Huang W, et al. Among authors: haynes ac. Pancreatology. 2017 Sep-Oct;17(5):689-697. doi: 10.1016/j.pan.2017.06.005. Epub 2017 Jun 10. Pancreatology. 2017. PMID: 28648518

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