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Increased Monocyte-Derived CD11b+ Macrophage Subpopulations Following Cigarette Smoke Exposure Are Associated With Impaired Bleomycin-Induced Tissue Remodelling.
Cass SP, Mekhael O, Thayaparan D, McGrath JJC, Revill SD, Fantauzzi MF, Wang P, Reihani A, Hayat AI, Stevenson CS, Dvorkin-Gheva A, Botelho FM, Stämpfli MR, Ask K. Cass SP, et al. Among authors: hayat ai. Front Immunol. 2021 Sep 16;12:740330. doi: 10.3389/fimmu.2021.740330. eCollection 2021. Front Immunol. 2021. PMID: 34603325 Free PMC article.
Cell-specific drug targeting in the lung.
Abed S, Turner R, Serniuck N, Tat V, Naiel S, Hayat A, Mekhael O, Vierhout M, Ask K, Rullo AF. Abed S, et al. Biochem Pharmacol. 2021 Aug;190:114577. doi: 10.1016/j.bcp.2021.114577. Epub 2021 Apr 19. Biochem Pharmacol. 2021. PMID: 33887259 Review.
Mouse Models of Lung Fibrosis.
Mekhael O, Naiel S, Vierhout M, Hayat AI, Revill SD, Abed S, Inman MD, Kolb MRJ, Ask K. Mekhael O, et al. Among authors: hayat ai. Methods Mol Biol. 2021;2299:291-321. doi: 10.1007/978-1-0716-1382-5_21. Methods Mol Biol. 2021. PMID: 34028751
Myeloid-specific deletion of activating transcription factor 6 alpha increases CD11b+ macrophage subpopulations and aggravates lung fibrosis.
Mekhael O, Revill SD, Hayat AI, Cass SP, MacDonald K, Vierhout M, Ayoub A, Reihani A, Padwal M, Imani J, Ayaub E, Yousof T, Dvorkin-Gheva A, Rullo A, Hirota JA, Richards CD, Bridgewater D, Stämpfli MR, Hambly N, Naqvi A, Kolb MR, Ask K. Mekhael O, et al. Among authors: hayat ai. Immunol Cell Biol. 2023 May;101(5):412-427. doi: 10.1111/imcb.12637. Epub 2023 Apr 4. Immunol Cell Biol. 2023. PMID: 36862017