Hawkins PT - Search Results

1

The synthetic TRPML1 agonist ML-SA1 rescues Alzheimer-related alterations of the endosomal-autophagic-lysosomal system.

Somogyi A, Kirkham ED, Lloyd-Evans E, Winston J, Allen ND, Mackrill JJ, Anderson KE, Hawkins PT, Gardiner SE, Waller-Evans H, Sims R, Boland B, O'Neill C. Somogyi A, et al. Among authors: hawkins pt. J Cell Sci. 2023 Mar 15;136(6):jcs259875. doi: 10.1242/jcs.259875. Epub 2023 Mar 21. J Cell Sci. 2023. PMID: 36825945 Free PMC article.

2

PtdIns3P binding to the PX domain of p40phox is a physiological signal in NADPH oxidase activation.

Ellson C, Davidson K, Anderson K, Stephens LR, Hawkins PT. Ellson C, et al. Among authors: hawkins pt. EMBO J. 2006 Oct 4;25(19):4468-78. doi: 10.1038/sj.emboj.7601346. Epub 2006 Sep 21. EMBO J. 2006. PMID: 16990793 Free PMC article.

3

Use of the GRP1 PH domain as a tool to measure the relative levels of PtdIns(3,4,5)P3 through a protein-lipid overlay approach.

Guillou H, Lécureuil C, Anderson KE, Suire S, Ferguson GJ, Ellson CD, Gray A, Divecha N, Hawkins PT, Stephens LR. Guillou H, et al. Among authors: hawkins pt. J Lipid Res. 2007 Mar;48(3):726-32. doi: 10.1194/jlr.D600038-JLR200. Epub 2006 Nov 27. J Lipid Res. 2007. PMID: 17130283 Free article.

4

PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils.

Anderson KE, Chessa TA, Davidson K, Henderson RB, Walker S, Tolmachova T, Grys K, Rausch O, Seabra MC, Tybulewicz VL, Stephens LR, Hawkins PT. Anderson KE, et al. Among authors: hawkins pt. Blood. 2010 Dec 2;116(23):4978-89. doi: 10.1182/blood-2010-03-275602. Epub 2010 Sep 2. Blood. 2010. PMID: 20813901 Free PMC article.

5

Phosphorylation of threonine 154 in p40phox is an important physiological signal for activation of the neutrophil NADPH oxidase.

Chessa TA, Anderson KE, Hu Y, Xu Q, Rausch O, Stephens LR, Hawkins PT. Chessa TA, et al. Among authors: hawkins pt. Blood. 2010 Dec 23;116(26):6027-36. doi: 10.1182/blood-2010-08-300889. Epub 2010 Sep 22. Blood. 2010. PMID: 20861461 Free PMC article.

6

Quantification of PtdInsP3 molecular species in cells and tissues by mass spectrometry.

Clark J, Anderson KE, Juvin V, Smith TS, Karpe F, Wakelam MJ, Stephens LR, Hawkins PT. Clark J, et al. Among authors: hawkins pt. Nat Methods. 2011 Mar;8(3):267-72. doi: 10.1038/nmeth.1564. Epub 2011 Jan 30. Nat Methods. 2011. PMID: 21278744 Free PMC article.

7

Structure of lipid kinase p110β/p85β elucidates an unusual SH2-domain-mediated inhibitory mechanism.

Zhang X, Vadas O, Perisic O, Anderson KE, Clark J, Hawkins PT, Stephens LR, Williams RL. Zhang X, et al. Among authors: hawkins pt. Mol Cell. 2011 Mar 4;41(5):567-78. doi: 10.1016/j.molcel.2011.01.026. Mol Cell. 2011. PMID: 21362552 Free PMC article.

8

The GTPase-activating protein ARAP3 regulates chemotaxis and adhesion-dependent processes in neutrophils.

Gambardella L, Anderson KE, Nussbaum C, Segonds-Pichon A, Margarido T, Norton L, Ludwig T, Sperandio M, Hawkins PT, Stephens L, Vermeren S. Gambardella L, et al. Among authors: hawkins pt. Blood. 2011 Jul 28;118(4):1087-98. doi: 10.1182/blood-2010-10-312959. Epub 2011 Apr 13. Blood. 2011. PMID: 21490342 Free article.

9

Lysophosphatidylinositol-acyltransferase-1 (LPIAT1) is required to maintain physiological levels of PtdIns and PtdInsP(2) in the mouse.

Anderson KE, Kielkowska A, Durrant TN, Juvin V, Clark J, Stephens LR, Hawkins PT. Anderson KE, et al. Among authors: hawkins pt. PLoS One. 2013;8(3):e58425. doi: 10.1371/journal.pone.0058425. Epub 2013 Mar 5. PLoS One. 2013. PMID: 23472195 Free PMC article.

10

A new approach to measuring phosphoinositides in cells by mass spectrometry.

Kielkowska A, Niewczas I, Anderson KE, Durrant TN, Clark J, Stephens LR, Hawkins PT. Kielkowska A, et al. Among authors: hawkins pt. Adv Biol Regul. 2014 Jan;54:131-41. doi: 10.1016/j.jbior.2013.09.001. Epub 2013 Sep 17. Adv Biol Regul. 2014. PMID: 24120934 Free article. Review.

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