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Page 1
FGF23 neutralization improves chronic kidney disease-associated hyperparathyroidism yet increases mortality.
Shalhoub V, Shatzen EM, Ward SC, Davis J, Stevens J, Bi V, Renshaw L, Hawkins N, Wang W, Chen C, Tsai MM, Cattley RC, Wronski TJ, Xia X, Li X, Henley C, Eschenberg M, Richards WG. Shalhoub V, et al. Among authors: hawkins n. J Clin Invest. 2012 Jul;122(7):2543-53. doi: 10.1172/JCI61405. Epub 2012 Jun 25. J Clin Invest. 2012. PMID: 22728934 Free PMC article.
FGF21 N- and C-termini play different roles in receptor interaction and activation.
Yie J, Hecht R, Patel J, Stevens J, Wang W, Hawkins N, Steavenson S, Smith S, Winters D, Fisher S, Cai L, Belouski E, Chen C, Michaels ML, Li YS, Lindberg R, Wang M, Véniant M, Xu J. Yie J, et al. Among authors: hawkins n. FEBS Lett. 2009 Jan 5;583(1):19-24. doi: 10.1016/j.febslet.2008.11.023. Epub 2008 Dec 4. FEBS Lett. 2009. PMID: 19059246 Free article.
Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL.
Kostenuik PJ, Nguyen HQ, McCabe J, Warmington KS, Kurahara C, Sun N, Chen C, Li L, Cattley RC, Van G, Scully S, Elliott R, Grisanti M, Morony S, Tan HL, Asuncion F, Li X, Ominsky MS, Stolina M, Dwyer D, Dougall WC, Hawkins N, Boyle WJ, Simonet WS, Sullivan JK. Kostenuik PJ, et al. Among authors: hawkins n. J Bone Miner Res. 2009 Feb;24(2):182-95. doi: 10.1359/jbmr.081112. J Bone Miner Res. 2009. PMID: 19016581 Free article.
C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors.
Wu X, Lemon B, Li X, Gupte J, Weiszmann J, Stevens J, Hawkins N, Shen W, Lindberg R, Chen JL, Tian H, Li Y. Wu X, et al. Among authors: hawkins n. J Biol Chem. 2008 Nov 28;283(48):33304-9. doi: 10.1074/jbc.M803319200. Epub 2008 Oct 1. J Biol Chem. 2008. PMID: 18829467 Free PMC article.
Characterization of osteoclast precursors in human blood.
Shalhoub V, Elliott G, Chiu L, Manoukian R, Kelley M, Hawkins N, Davy E, Shimamoto G, Beck J, Kaufman SA, Van G, Scully S, Qi M, Grisanti M, Dunstan C, Boyle WJ, Lacey DL. Shalhoub V, et al. Among authors: hawkins n. Br J Haematol. 2000 Nov;111(2):501-12. doi: 10.1046/j.1365-2141.2000.02379.x. Br J Haematol. 2000. PMID: 11122091 Free article.
Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice.
Khare SD, Sarosi I, Xia XZ, McCabe S, Miner K, Solovyev I, Hawkins N, Kelley M, Chang D, Van G, Ross L, Delaney J, Wang L, Lacey D, Boyle WJ, Hsu H. Khare SD, et al. Among authors: hawkins n. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3370-5. doi: 10.1073/pnas.97.7.3370. Proc Natl Acad Sci U S A. 2000. PMID: 10716715 Free PMC article.
Co-receptor requirements for fibroblast growth factor-19 signaling.
Wu X, Ge H, Gupte J, Weiszmann J, Shimamoto G, Stevens J, Hawkins N, Lemon B, Shen W, Xu J, Veniant MM, Li YS, Lindberg R, Chen JL, Tian H, Li Y. Wu X, et al. Among authors: hawkins n. J Biol Chem. 2007 Oct 5;282(40):29069-72. doi: 10.1074/jbc.C700130200. Epub 2007 Aug 21. J Biol Chem. 2007. PMID: 17711860 Free article.
750 results