Hawkins E - Search Results

1

Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formation.

Sperlazza J, Rahmani M, Beckta J, Aust M, Hawkins E, Wang SZ, Zu Zhu S, Podder S, Dumur C, Archer K, Grant S, Ginder GD. Sperlazza J, et al. Among authors: hawkins e. Blood. 2015 Sep 17;126(12):1462-72. doi: 10.1182/blood-2015-03-631606. Epub 2015 Aug 11. Blood. 2015. PMID: 26265695 Free PMC article.

2

Co-administration of the mTORC1/TORC2 inhibitor INK128 and the Bcl-2/Bcl-xL antagonist ABT-737 kills human myeloid leukemia cells through Mcl-1 down-regulation and AKT inactivation.

Rahmani M, Aust MM, Hawkins E, Parker RE, Ross M, Kmieciak M, Reshko LB, Rizzo KA, Dumur CI, Ferreira-Gonzalez A, Grant S. Rahmani M, et al. Among authors: hawkins e. Haematologica. 2015 Dec;100(12):1553-63. doi: 10.3324/haematol.2015.130351. Epub 2015 Oct 9. Haematologica. 2015. PMID: 26452980 Free PMC article.

3

Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells.

Rahmani M, Nkwocha J, Hawkins E, Pei X, Parker RE, Kmieciak M, Leverson JD, Sampath D, Ferreira-Gonzalez A, Grant S. Rahmani M, et al. Among authors: hawkins e. Cancer Res. 2018 Jun 1;78(11):3075-3086. doi: 10.1158/0008-5472.CAN-17-3024. Epub 2018 Mar 20. Cancer Res. 2018. PMID: 29559471 Free PMC article.

4

Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin's lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms.

Nguyen T, Parker R, Hawkins E, Holkova B, Yazbeck V, Kolluri A, Kmieciak M, Rahmani M, Grant S. Nguyen T, et al. Among authors: hawkins e. Oncotarget. 2017 May 9;8(19):31478-31493. doi: 10.18632/oncotarget.15649. Oncotarget. 2017. PMID: 28416758 Free PMC article.

5

Synergism between bosutinib (SKI-606) and the Chk1 inhibitor (PF-00477736) in highly imatinib-resistant BCR/ABL⁺ leukemia cells.

Nguyen T, Hawkins E, Kolluri A, Kmieciak M, Park H, Lin H, Grant S. Nguyen T, et al. Among authors: hawkins e. Leuk Res. 2015 Jan;39(1):65-71. doi: 10.1016/j.leukres.2014.10.009. Epub 2014 Nov 11. Leuk Res. 2015. PMID: 25465126 Free PMC article.

6

Homoharringtonine interacts synergistically with bortezomib in NHL cells through MCL-1 and NOXA-dependent mechanisms.

Nguyen T, Parker R, Zhang Y, Hawkins E, Kmieciak M, Craun W, Grant S. Nguyen T, et al. Among authors: hawkins e. BMC Cancer. 2018 Nov 16;18(1):1129. doi: 10.1186/s12885-018-5018-x. BMC Cancer. 2018. PMID: 30445933 Free PMC article.

7

Correction: Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin's lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms.

Nguyen T, Parker R, Hawkins E, Holkova B, Yazbeck V, Kolluri A, Kmieciak M, Rahmani M, Grant S. Nguyen T, et al. Among authors: hawkins e. Oncotarget. 2019 Sep 3;10(51):5383-5384. doi: 10.18632/oncotarget.27175. eCollection 2019 Sep 3. Oncotarget. 2019. PMID: 31523396 Free PMC article.

8

Epigenetic histone acetylation and Bdnf dysregulation in the hippocampus of rats exposed to repeated, low-dose diisopropylfluorophosphate.

Ribeiro ACR, Jahr FM, Hawkins E, Kronfol MM, Younis RM, McClay JL, Deshpande LS. Ribeiro ACR, et al. Among authors: hawkins e. Life Sci. 2021 Sep 15;281:119765. doi: 10.1016/j.lfs.2021.119765. Epub 2021 Jun 26. Life Sci. 2021. PMID: 34186043

9

Molecular mechanisms for the antidepressant-like effects of a low-dose ketamine treatment in a DFP-based rat model for Gulf War Illness.

Ribeiro ACR, Zhu J, Kronfol MM, Jahr FM, Younis RM, Hawkins E, McClay JL, Deshpande LS. Ribeiro ACR, et al. Among authors: hawkins e. Neurotoxicology. 2020 Sep;80:52-59. doi: 10.1016/j.neuro.2020.06.011. Epub 2020 Jun 24. Neurotoxicology. 2020. PMID: 32592718 Free article.

10

Assessment of Ketamine and Its Enantiomers in an Organophosphate-Based Rat Model for Features of Gulf War Illness.

Zhu J, Hawkins E, Phillips K, Deshpande LS. Zhu J, et al. Among authors: hawkins e. Int J Environ Res Public Health. 2020 Jun 30;17(13):4710. doi: 10.3390/ijerph17134710. Int J Environ Res Public Health. 2020. PMID: 32629972 Free PMC article.

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