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Muscle weakness and mitochondrial stress occur before metastasis in a novel mouse model of ovarian cancer cachexia.
Delfinis LJ, Ogilvie LM, Khajehzadehshoushtar S, Gandhi S, Garibotti MC, Thuhan AK, Matuszewska K, Pereira M, Jones RG 3rd, Cheng AJ, Hawke TJ, Greene NP, Murach KA, Simpson JA, Petrik J, Perry CGR. Delfinis LJ, et al. Among authors: hawke tj. bioRxiv [Preprint]. 2024 Apr 8:2024.04.08.588639. doi: 10.1101/2024.04.08.588639. bioRxiv. 2024. PMID: 38645227 Free PMC article. Preprint.
The slow-release adiponectin analog ALY688-SR modifies early-stage disease development in the D2.mdx mouse model of Duchenne muscular dystrophy.
Bellissimo CA, Gandhi S, Castellani LN, Murugathasan M, Delfinis LJ, Thuhan A, Garibotti MC, Seo Y, Rebalka IA, Hsu HH, Sweeney G, Hawke TJ, Abdul-Sater AA, Perry CGR. Bellissimo CA, et al. Among authors: hawke tj. Am J Physiol Cell Physiol. 2024 Apr 1;326(4):C1011-C1026. doi: 10.1152/ajpcell.00638.2023. Epub 2023 Dec 25. Am J Physiol Cell Physiol. 2024. PMID: 38145301
Therapeutic targeting of mitochondria in muscular dystrophies. Editorial focus on: "Mitochondrial creatine sensitivity is lost in the D2.mdx model of Duchenne muscular dystrophy and rescued by the mitochondrial-enhancing compound Olesoxime".
Juracic ES, Brahmbhatt AN, Hawke TJ. Juracic ES, et al. Among authors: hawke tj. Am J Physiol Cell Physiol. 2023 Aug 1;325(2):C563-C564. doi: 10.1152/ajpcell.00301.2023. Epub 2023 Jul 17. Am J Physiol Cell Physiol. 2023. PMID: 37458438 No abstract available.
GDF15 promotes weight loss by enhancing energy expenditure in muscle.
Wang D, Townsend LK, DesOrmeaux GJ, Frangos SM, Batchuluun B, Dumont L, Kuhre RE, Ahmadi E, Hu S, Rebalka IA, Gautam J, Jabile MJT, Pileggi CA, Rehal S, Desjardins EM, Tsakiridis EE, Lally JSV, Juracic ES, Tupling AR, Gerstein HC, Paré G, Tsakiridis T, Harper ME, Hawke TJ, Speakman JR, Blondin DP, Holloway GP, Jørgensen SB, Steinberg GR. Wang D, et al. Among authors: hawke tj. Nature. 2023 Jul;619(7968):143-150. doi: 10.1038/s41586-023-06249-4. Epub 2023 Jun 28. Nature. 2023. PMID: 37380764 Free PMC article.
American Journal of Physiology-Cell Physiology in 2022: at a glance.
Delpire E, Hawke TJ, Karthikeyan M, Kong W, Nyström A, Uchida S, Schaefer L. Delpire E, et al. Among authors: hawke tj. Am J Physiol Cell Physiol. 2023 Feb 1;324(2):C553-C557. doi: 10.1152/ajpcell.00009.2023. Epub 2023 Jan 16. Am J Physiol Cell Physiol. 2023. PMID: 36645665 Free article. No abstract available.
114 results