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161 results

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Page 1
T cell cholesterol efflux suppresses apoptosis and senescence and increases atherosclerosis in middle aged mice.
Bazioti V, La Rose AM, Maassen S, Bianchi F, de Boer R, Halmos B, Dabral D, Guilbaud E, Flohr-Svendsen A, Groenen AG, Marmolejo-Garza A, Koster MH, Kloosterhuis NJ, Havinga R, Pranger AT, Langelaar-Makkinje M, de Bruin A, van de Sluis B, Kohan AB, Yvan-Charvet L, van den Bogaart G, Westerterp M. Bazioti V, et al. Among authors: havinga r. Nat Commun. 2022 Jul 1;13(1):3799. doi: 10.1038/s41467-022-31135-4. Nat Commun. 2022. PMID: 35778407 Free PMC article.
Cholesterol-induced hepatic inflammation does not underlie the predisposition to insulin resistance in dyslipidemic female LDL receptor knockout mice.
Gruben N, Funke A, Kloosterhuis NJ, Schreurs M, Sheedfar F, Havinga R, Houten SM, Shiri-Sverdlov R, van de Sluis B, Kuivenhoven JA, Koonen DP, Hofker MH. Gruben N, et al. Among authors: havinga r. J Diabetes Res. 2015;2015:956854. doi: 10.1155/2015/956854. Epub 2015 Feb 28. J Diabetes Res. 2015. PMID: 25815343 Free PMC article.
LED-phototherapy does not induce oxidative DNA damage in hyperbilirubinemic Gunn rats.
van der Schoor LWE, Hulzebos CV, van Faassen MH, Kema IP, de Bruin A, Havinga R, Koster M, Youssef SA, Bongiovanni L, Jonker JW, Verkade HJ. van der Schoor LWE, et al. Among authors: havinga r. Pediatr Res. 2019 Jun;85(7):1041-1047. doi: 10.1038/s41390-019-0367-y. Epub 2019 Mar 9. Pediatr Res. 2019. PMID: 30851724
Spontaneous liver disease in wild-type C57BL/6JOlaHsd mice fed semisynthetic diet.
Ronda OAHO, van de Heijning BJM, de Bruin A, Thomas RE, Martini I, Koehorst M, Gerding A, Koster MH, Bloks VW, Jurdzinski A, Mulder NL, Havinga R, van der Beek EM, Reijngoud DJ, Kuipers F, Verkade HJ. Ronda OAHO, et al. Among authors: havinga r. PLoS One. 2020 Sep 21;15(9):e0232069. doi: 10.1371/journal.pone.0232069. eCollection 2020. PLoS One. 2020. PMID: 32956351 Free PMC article.
The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis.
Heida A, Gruben N, Catrysse L, Koehorst M, Koster M, Kloosterhuis NJ, Gerding A, Havinga R, Bloks VW, Bongiovanni L, Wolters JC, van Dijk T, van Loo G, de Bruin A, Kuipers F, Koonen DPY, van de Sluis B. Heida A, et al. Among authors: havinga r. Mol Metab. 2021 Dec;54:101349. doi: 10.1016/j.molmet.2021.101349. Epub 2021 Oct 6. Mol Metab. 2021. PMID: 34626855 Free PMC article.
Increased atherosclerosis in a mouse model of glycogen storage disease type 1a.
La Rose AM, Groenen AG, Halmos B, Bazioti V, Rutten MGS, Krishnamurthy KA, Koster MH, Kloosterhuis NJ, Smit M, Havinga R, Mithieux G, Rajas F, Kuipers F, Oosterveer MH, Westerterp M. La Rose AM, et al. Among authors: havinga r. Mol Genet Metab Rep. 2022 Apr 21;31:100872. doi: 10.1016/j.ymgmr.2022.100872. eCollection 2022 Jun. Mol Genet Metab Rep. 2022. PMID: 35782606 Free PMC article.
Pharmacological inhibition of MEK1/2 signaling disrupts bile acid metabolism through loss of Shp and enhanced Cyp7a1 expression.
Verzijl CRC, van de Peppel IP, Eilers RE, Bloks VW, Wolters JC, Koehorst M, Kloosterhuis NJ, Havinga R, Jalving M, Struik D, Jonker JW. Verzijl CRC, et al. Among authors: havinga r. Biomed Pharmacother. 2023 Mar;159:114270. doi: 10.1016/j.biopha.2023.114270. Epub 2023 Jan 19. Biomed Pharmacother. 2023. PMID: 36680812 Free article.
Hyperglycaemia, pregnancy outcomes and maternal metabolic disease risk during pregnancy and lactation in a lean gestational diabetes mouse model.
Tol AJC, Hribar K, Kruit J, Bongiovanni L, Vieira-Lara MA, Koster MH, Kloosterhuis NJ, Havinga R, Koehorst M, de Bruin A, Bakker BM, Oosterveer MH, van der Beek EM. Tol AJC, et al. Among authors: havinga r. J Physiol. 2023 May;601(10):1761-1780. doi: 10.1113/JP284061. Epub 2023 Apr 18. J Physiol. 2023. PMID: 37010236 Free article.
The chemotherapeutic drug doxorubicin does not exacerbate p16Ink4a-positive senescent cell accumulation and cardiometabolic disease development in young adult female LDLR-deficient mice.
Postmus AC, Kruit JK, Eilers RE, Havinga R, Koster MH, Johmura Y, Nakanishi M, van de Sluis B, Jonker JW. Postmus AC, et al. Among authors: havinga r. Toxicol Appl Pharmacol. 2023 Jun 1;468:116531. doi: 10.1016/j.taap.2023.116531. Epub 2023 Apr 23. Toxicol Appl Pharmacol. 2023. PMID: 37088304 Free article.
Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice.
Heida A, van Dijk T, Smit M, Koehorst M, Koster M, Kloosterhuis N, Havinga R, Bloks VW, Wolters JC, de Bruin A, Kuivenhoven JA, de Boer JF, Kuipers F, van de Sluis B. Heida A, et al. Among authors: havinga r. Biochim Biophys Acta Mol Cell Biol Lipids. 2024 Mar;1869(2):159445. doi: 10.1016/j.bbalip.2023.159445. Epub 2023 Dec 11. Biochim Biophys Acta Mol Cell Biol Lipids. 2024. PMID: 38086439 Free article.
161 results