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Anaerobutyricum soehngenii Reduces Hepatic Lipogenic Pathways and Increases Intestinal Gluconeogenic Gene Expression in Metabolic-Dysfunction-Associated Steatotic Liver Disease (MASLD) Mice.
Mak AL, Augustijn QJJ, Heymann CJF, Havik S, Verdoes X, Rios-Morales M, Bosmans LA, Verheij J, Meijnikman AS, de Jonge PA, Herrema H, de Vos WM, Nieuwdorp M, Grefhorst A, Holleboom AG. Mak AL, et al. Among authors: havik s. Int J Mol Sci. 2024 Mar 20;25(6):3481. doi: 10.3390/ijms25063481. Int J Mol Sci. 2024. PMID: 38542455 Free PMC article.
Diacylglycerols and Lysophosphatidic Acid, Enriched on Lipoprotein(a), Contribute to Monocyte Inflammation.
Dzobo KE, Cupido AJ, Mol BM, Stiekema LCA, Versloot M, Winkelmeijer M, Peter J, Pennekamp AM, Havik SR, Vaz FM, van Weeghel M, Prange KHM, Levels JHM, de Winther MPJ, Tsimikas S, Groen AK, Stroes ESG, de Kleijn DPV, Kroon J. Dzobo KE, et al. Among authors: havik sr. Arterioscler Thromb Vasc Biol. 2024 Mar;44(3):720-740. doi: 10.1161/ATVBAHA.123.319937. Epub 2024 Jan 25. Arterioscler Thromb Vasc Biol. 2024. PMID: 38269588 Free PMC article.
Pyrrolopyrimidine based CSF1R inhibitors: Attempted departure from Flatland.
Bjørnstad F, Havik S, Aarhus TI, Mahdi I, Unger A, Habenberger P, Degenhart C, Eickhoff J, Klebl BM, Sundby E, Hoff BH. Bjørnstad F, et al. Among authors: havik s. Eur J Med Chem. 2024 Feb 5;265:116053. doi: 10.1016/j.ejmech.2023.116053. Epub 2023 Dec 17. Eur J Med Chem. 2024. PMID: 38141285 Free article.
Intestinal permeability is associated with aggravated inflammation and myofibroblast accumulation in Graves' orbitopathy: the MicroGO study.
Fenneman AC, van der Spek AH, Hartstra A, Havik S, Salonen A, de Vos WM, Soeters MR, Saeed P, Nieuwdorp M, Rampanelli E. Fenneman AC, et al. Among authors: havik s. Front Endocrinol (Lausanne). 2023 Nov 30;14:1173481. doi: 10.3389/fendo.2023.1173481. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 38107520 Free PMC article.
Gut-derived bacterial flagellin induces beta-cell inflammation and dysfunction.
Scheithauer TPM, Herrema H, Yu H, Bakker GJ, Winkelmeijer M, Soukhatcheva G, Dai D, Ma C, Havik SR, Balvers M, Davids M, Meijnikman AS, Aydin Ö, van den Born BH, Besselink MG, Busch OR, de Brauw M, van de Laar A, Belzer C, Stahl M, de Vos WM, Vallance BA, Nieuwdorp M, Verchere CB, van Raalte DH. Scheithauer TPM, et al. Among authors: havik sr. Gut Microbes. 2022 Jan-Dec;14(1):2111951. doi: 10.1080/19490976.2022.2111951. Gut Microbes. 2022. PMID: 35984746 Free PMC article.
Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study.
Koopen A, Witjes J, Wortelboer K, Majait S, Prodan A, Levin E, Herrema H, Winkelmeijer M, Aalvink S, Bergman JJGHM, Havik S, Hartmann B, Levels H, Bergh PO, van Son J, Balvers M, Bastos DM, Stroes E, Groen AK, Henricsson M, Kemper EM, Holst J, Strauch CM, Hazen SL, Bäckhed F, De Vos WM, Nieuwdorp M, Rampanelli E. Koopen A, et al. Among authors: havik s. Gut. 2022 Aug;71(8):1577-1587. doi: 10.1136/gutjnl-2020-323297. Epub 2021 Oct 25. Gut. 2022. PMID: 34697034 Free PMC article. Clinical Trial.
Infusion of donor feces affects the gut-brain axis in humans with metabolic syndrome.
Hartstra AV, Schüppel V, Imangaliyev S, Schrantee A, Prodan A, Collard D, Levin E, Dallinga-Thie G, Ackermans MT, Winkelmeijer M, Havik SR, Metwaly A, Lagkouvardos I, Nier A, Bergheim I, Heikenwalder M, Dunkel A, Nederveen AJ, Liebisch G, Mancano G, Claus SP, Benítez-Páez A, la Fleur SE, Bergman JJ, Gerdes V, Sanz Y, Booij J, Kemper E, Groen AK, Serlie MJ, Haller D, Nieuwdorp M. Hartstra AV, et al. Among authors: havik sr. Mol Metab. 2020 Dec;42:101076. doi: 10.1016/j.molmet.2020.101076. Epub 2020 Sep 8. Mol Metab. 2020. PMID: 32916306 Free PMC article. Clinical Trial.
Genetic variants in SUSD2 are associated with the risk of ischemic heart disease.
Bruikman CS, Dalila N, van Capelleveen JC, Kroon J, Peter J, Havik SR, Willems M, Huisman LC, de Boer OJ, Hovingh GK, Tybjaerg-Hansen A, Dallinga-Thie GM. Bruikman CS, et al. Among authors: havik sr. J Clin Lipidol. 2020 Jul-Aug;14(4):470-481. doi: 10.1016/j.jacl.2020.05.100. Epub 2020 Jun 3. J Clin Lipidol. 2020. PMID: 32620384
24 results