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Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development.
Berbée JF, Boon MR, Khedoe PP, Bartelt A, Schlein C, Worthmann A, Kooijman S, Hoeke G, Mol IM, John C, Jung C, Vazirpanah N, Brouwers LP, Gordts PL, Esko JD, Hiemstra PS, Havekes LM, Scheja L, Heeren J, Rensen PC. Berbée JF, et al. Among authors: havekes lm. Nat Commun. 2015 Mar 10;6:6356. doi: 10.1038/ncomms7356. Nat Commun. 2015. PMID: 25754609 Free PMC article.
Brown adipose tissue takes up plasma triglycerides mostly after lipolysis.
Khedoe PP, Hoeke G, Kooijman S, Dijk W, Buijs JT, Kersten S, Havekes LM, Hiemstra PS, Berbée JF, Boon MR, Rensen PC. Khedoe PP, et al. Among authors: havekes lm. J Lipid Res. 2015 Jan;56(1):51-9. doi: 10.1194/jlr.M052746. Epub 2014 Oct 28. J Lipid Res. 2015. PMID: 25351615 Free PMC article.
Ritonavir protects against the development of atherosclerosis in APOE*3-Leiden mice.
den Boer MA, Westerterp M, de Vries-van der Weij J, Wang Y, Hu L, Espirito Santo SM, Kooistra T, Reiss P, Romijn JA, Havekes LM, Rensen PC. den Boer MA, et al. Among authors: havekes lm. Atherosclerosis. 2010 Jun;210(2):381-7. doi: 10.1016/j.atherosclerosis.2009.11.043. Epub 2009 Dec 1. Atherosclerosis. 2010. PMID: 20060117
Resveratrol protects against atherosclerosis, but does not add to the antiatherogenic effect of atorvastatin, in APOE*3-Leiden.CETP mice.
Berbée JF, Wong MC, Wang Y, van der Hoorn JW, Khedoe PP, van Klinken JB, Mol IM, Hiemstra PS, Tsikas D, Romijn JA, Havekes LM, Princen HM, Rensen PC. Berbée JF, et al. Among authors: havekes lm. J Nutr Biochem. 2013 Aug;24(8):1423-30. doi: 10.1016/j.jnutbio.2012.11.009. Epub 2013 Jan 18. J Nutr Biochem. 2013. PMID: 23337345
BMP7 activates brown adipose tissue and reduces diet-induced obesity only at subthermoneutrality.
Boon MR, van den Berg SA, Wang Y, van den Bossche J, Karkampouna S, Bauwens M, De Saint-Hubert M, van der Horst G, Vukicevic S, de Winther MP, Havekes LM, Jukema JW, Tamsma JT, van der Pluijm G, van Dijk KW, Rensen PC. Boon MR, et al. Among authors: havekes lm. PLoS One. 2013 Sep 16;8(9):e74083. doi: 10.1371/journal.pone.0074083. eCollection 2013. PLoS One. 2013. PMID: 24066098 Free PMC article.
448 results