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Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1.
Kang SY, Halvorsen OJ, Gravdal K, Bhattacharya N, Lee JM, Liu NW, Johnston BT, Johnston AB, Haukaas SA, Aamodt K, Yoo S, Akslen LA, Watnick RS. Kang SY, et al. Among authors: haukaas sa. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12115-20. doi: 10.1073/pnas.0903120106. Epub 2009 Jul 6. Proc Natl Acad Sci U S A. 2009. PMID: 19581582 Free PMC article.
Bone marrow-derived Gr1+ cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1.
Catena R, Bhattacharya N, El Rayes T, Wang S, Choi H, Gao D, Ryu S, Joshi N, Bielenberg D, Lee SB, Haukaas SA, Gravdal K, Halvorsen OJ, Akslen LA, Watnick RS, Mittal V. Catena R, et al. Among authors: haukaas sa. Cancer Discov. 2013 May;3(5):578-89. doi: 10.1158/2159-8290.CD-12-0476. Epub 2013 Apr 30. Cancer Discov. 2013. PMID: 23633432 Free PMC article.
68 results