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Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound.
Yoo SW, Waheed AA, Deme P, Tohumeken S, Rais R, Smith MD, DeMarino C, Calabresi PA, Kashanchi F, Freed EO, Slusher BS, Haughey NJ. Yoo SW, et al. Among authors: haughey nj. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2219543120. doi: 10.1073/pnas.2219543120. Epub 2023 Jul 5. Proc Natl Acad Sci U S A. 2023. PMID: 37406092 Free PMC article.
Granzyme B mediates neurotoxicity through a G-protein-coupled receptor.
Wang T, Allie R, Conant K, Haughey N, Turchan-Chelowo J, Hahn K, Rosen A, Steiner J, Keswani S, Jones M, Calabresi PA, Nath A. Wang T, et al. FASEB J. 2006 Jun;20(8):1209-11. doi: 10.1096/fj.05-5022fje. Epub 2006 Apr 24. FASEB J. 2006. PMID: 16636104
A lipid storage-like disorder contributes to cognitive decline in HIV-infected subjects.
Bandaru VV, Mielke MM, Sacktor N, McArthur JC, Grant I, Letendre S, Chang L, Wojna V, Pardo C, Calabresi P, Munsaka S, Haughey NJ. Bandaru VV, et al. Among authors: haughey nj. Neurology. 2013 Oct 22;81(17):1492-9. doi: 10.1212/WNL.0b013e3182a9565e. Epub 2013 Sep 11. Neurology. 2013. PMID: 24027056 Free PMC article.
Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics.
Vidaurre OG, Haines JD, Katz Sand I, Adula KP, Huynh JL, McGraw CA, Zhang F, Varghese M, Sotirchos E, Bhargava P, Bandaru VV, Pasinetti G, Zhang W, Inglese M, Calabresi PA, Wu G, Miller AE, Haughey NJ, Lublin FD, Casaccia P. Vidaurre OG, et al. Among authors: haughey nj. Brain. 2014 Aug;137(Pt 8):2271-86. doi: 10.1093/brain/awu139. Epub 2014 Jun 3. Brain. 2014. PMID: 24893707 Free PMC article.
Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties.
Figuera-Losada M, Stathis M, Dorskind JM, Thomas AG, Bandaru VV, Yoo SW, Westwood NJ, Rogers GW, McArthur JC, Haughey NJ, Slusher BS, Rojas C. Figuera-Losada M, et al. Among authors: haughey nj. PLoS One. 2015 May 26;10(5):e0124481. doi: 10.1371/journal.pone.0124481. eCollection 2015. PLoS One. 2015. PMID: 26010541 Free PMC article.
Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions.
Dickens AM, Tovar-Y-Romo LB, Yoo SW, Trout AL, Bae M, Kanmogne M, Megra B, Williams DW, Witwer KW, Gacias M, Tabatadze N, Cole RN, Casaccia P, Berman JW, Anthony DC, Haughey NJ. Dickens AM, et al. Among authors: haughey nj. Sci Signal. 2017 Apr 4;10(473):eaai7696. doi: 10.1126/scisignal.aai7696. Sci Signal. 2017. PMID: 28377412 Free PMC article.
The Psychiatric Impact of HIV.
Nedelcovych MT, Manning AA, Semenova S, Gamaldo C, Haughey NJ, Slusher BS. Nedelcovych MT, et al. Among authors: haughey nj. ACS Chem Neurosci. 2017 Jul 19;8(7):1432-1434. doi: 10.1021/acschemneuro.7b00169. Epub 2017 May 24. ACS Chem Neurosci. 2017. PMID: 28537385 Free PMC article.
171 results