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A-296G variant of THBS1 gene (rs1478605) is associated with a lower frequency of stroke in a Brazilian population with sickle cell anemia.
Oliveira JMF, Arcanjo GS, Domingos IF, Batista JVGF, Pereira-Martins DA, Batista THC, Hatzlhofer BLD, Falcão DA, Diniz MV, Silva AP, Pires BCV, Dos Anjos AC, Costa FF, Araujo AS, Lucena-Araujo AR, Bezerra MA. Oliveira JMF, et al. Among authors: hatzlhofer bld. J Stroke Cerebrovasc Dis. 2024 Jan;33(1):107474. doi: 10.1016/j.jstrokecerebrovasdis.2023.107474. Epub 2023 Nov 24. J Stroke Cerebrovasc Dis. 2024. PMID: 38006767
Alpha thalassemia, but not βS-globin haplotypes, influence sickle cell anemia clinical outcome in a large, single-center Brazilian cohort.
Hatzlhofer BLD, Pereira-Martins DA, de Farias Domingos I, Arcanjo GDS, Weinhäuser I, Falcão DA, Farias ICC, de Freitas Batista JVG, Prado LPL, Oliveira JMF, Batista THC, Sobreira MJVC, de Santana RM, Araújo ABS, de Melo MA, de Ancântara BV, Coelho-Silva JL, de Moura Rafael ABL, de Lima Silva DM, Albuquerque FP, Santos MNN, Dos Anjos AC, Costa FF, da Silva Araújo A, Lucena-Araújo AR, Bezerra MAC. Hatzlhofer BLD, et al. Ann Hematol. 2021 Apr;100(4):921-931. doi: 10.1007/s00277-021-04450-x. Epub 2021 Feb 13. Ann Hematol. 2021. PMID: 33586016
Association of the SOD2 Polymorphism (Val16Ala) and SOD Activity with Vaso-occlusive Crisis and Acute Splenic Sequestration in Children with Sickle Cell Anemia.
Farias ICC, Mendonça-Belmont TF, da Silva AS, do Ó KP, Ferreira F, Medeiros FS, da Silva Vasconcelos LR, Bezerra MAC, da Silva Araújo A, de Moura PMMF, Hatzlhofer BLD, Dos Anjos ACM, de Mendonça Cavalcanti MDS. Farias ICC, et al. Among authors: hatzlhofer bld. Mediterr J Hematol Infect Dis. 2018 Feb 21;10(1):e2018012. doi: 10.4084/MJHID.2018.012. eCollection 2018. Mediterr J Hematol Infect Dis. 2018. PMID: 29531649 Free PMC article.
Combined genotypes of the MBL2 gene related to low mannose-binding lectin levels are associated with vaso-occlusive events in children with sickle cell anemia.
Medeiros FS, Mendonça TF, Lopes KAM, França LMC, Silva AS, Vasconcelos LRS, Oliveira MCVC, Anjos ACM, Hatzlhofer BLD, Bezerra MAC, Araújo AS, Moura P, Cavalcanti MSM. Medeiros FS, et al. Among authors: hatzlhofer bld. Genet Mol Biol. 2017 Jul-Sep;40(3):600-603. doi: 10.1590/1678-4685-GMB-2016-0161. Epub 2017 Aug 21. Genet Mol Biol. 2017. PMID: 28837214 Free PMC article.
The CCR5Δ32 polymorphism in Brazilian patients with sickle cell disease.
Lopes MP, Santos MN, Faber EW, Bezerra MA, Hatzlhofer BL, Albuquerque DM, Zaccariotto TR, Ribeiro DM, Araújo Ada S, Costa FF, Sonati Mde F. Lopes MP, et al. Dis Markers. 2014;2014:678246. doi: 10.1155/2014/678246. Epub 2014 Nov 11. Dis Markers. 2014. PMID: 25548430 Free PMC article.
Erythropoiesis-driven regulation of hepcidin in human red cell disorders is better reflected through concentrations of soluble transferrin receptor rather than growth differentiation factor 15.
Fertrin KY, Lanaro C, Franco-Penteado CF, de Albuquerque DM, de Mello MR, Pallis FR, Bezerra MA, Hatzlhofer BL, Olbina G, Saad ST, da Silva Araújo A, Westerman M, Costa FF. Fertrin KY, et al. Am J Hematol. 2014 Apr;89(4):385-90. doi: 10.1002/ajh.23649. Am J Hematol. 2014. PMID: 24860871 Free article.
Association between the genetic polymorphisms of glutathione S-transferase (GSTM1 and GSTT1) and the clinical manifestations in sickle cell anemia.
de Oliveira Filho RA, Silva GJ, de Farias Domingos I, Hatzlhofer BL, da Silva Araújo A, de Lima Filho JL, Bezerra MA, Martins DB, de Araújo RF. de Oliveira Filho RA, et al. Blood Cells Mol Dis. 2013 Aug;51(2):76-9. doi: 10.1016/j.bcmd.2013.03.003. Epub 2013 Apr 13. Blood Cells Mol Dis. 2013. PMID: 23590899
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