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Selection of personalized patient therapy through the use of knowledge-based computational models that identify tumor-driving signal transduction pathways.
Verhaegh W, van Ooijen H, Inda MA, Hatzis P, Versteeg R, Smid M, Martens J, Foekens J, van de Wiel P, Clevers H, van de Stolpe A. Verhaegh W, et al. Among authors: hatzis p. Cancer Res. 2014 Jun 1;74(11):2936-45. doi: 10.1158/0008-5472.CAN-13-2515. Epub 2014 Apr 2. Cancer Res. 2014. PMID: 24695361 Free article.
Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells.
Hatzis P, van der Flier LG, van Driel MA, Guryev V, Nielsen F, Denissov S, Nijman IJ, Koster J, Santo EE, Welboren W, Versteeg R, Cuppen E, van de Wetering M, Clevers H, Stunnenberg HG. Hatzis P, et al. Mol Cell Biol. 2008 Apr;28(8):2732-44. doi: 10.1128/MCB.02175-07. Epub 2008 Feb 11. Mol Cell Biol. 2008. PMID: 18268006 Free PMC article.
Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma.
De Crignis E, Hossain T, Romal S, Carofiglio F, Moulos P, Khalid MM, Rao S, Bazrafshan A, Verstegen MM, Pourfarzad F, Koutsothanassis C, Gehart H, Kan TW, Palstra RJ, Boucher C, IJzermans JN, Huch M, Boj SF, Vries R, Clevers H, van der Laan LJ, Hatzis P, Mahmoudi T. De Crignis E, et al. Among authors: hatzis p. Elife. 2021 Jul 30;10:e60747. doi: 10.7554/eLife.60747. Elife. 2021. PMID: 34328417 Free PMC article.
Wnt signalling induces maturation of Paneth cells in intestinal crypts.
van Es JH, Jay P, Gregorieff A, van Gijn ME, Jonkheer S, Hatzis P, Thiele A, van den Born M, Begthel H, Brabletz T, Taketo MM, Clevers H. van Es JH, et al. Among authors: hatzis p. Nat Cell Biol. 2005 Apr;7(4):381-6. doi: 10.1038/ncb1240. Epub 2005 Mar 20. Nat Cell Biol. 2005. PMID: 15778706
Transcription factor achaete scute-like 2 controls intestinal stem cell fate.
van der Flier LG, van Gijn ME, Hatzis P, Kujala P, Haegebarth A, Stange DE, Begthel H, van den Born M, Guryev V, Oving I, van Es JH, Barker N, Peters PJ, van de Wetering M, Clevers H. van der Flier LG, et al. Among authors: hatzis p. Cell. 2009 Mar 6;136(5):903-12. doi: 10.1016/j.cell.2009.01.031. Cell. 2009. PMID: 19269367 Free article.
43 results