Hatcher NG - Search Results

1

Validation of a multiplexed and targeted lipidomics assay for accurate quantification of lipidomes.

Zhang NR, Hatcher NG, Ekroos K, Kedia K, Kandebo M, Marcus JN, Smith SM, Bateman KP, Spellman DS. Zhang NR, et al. Among authors: hatcher ng. J Lipid Res. 2022 Jun;63(6):100218. doi: 10.1016/j.jlr.2022.100218. Epub 2022 Apr 27. J Lipid Res. 2022. PMID: 35489416 Free PMC article.

2

Generic automated method for liquid chromatography-multiple reaction monitoring mass spectrometry based monoclonal antibody quantitation for preclinical pharmacokinetic studies.

Zhang Q, Spellman DS, Song Y, Choi B, Hatcher NG, Tomazela D, Beaumont M, Tabrizifard M, Prabhavalkar D, Seghezzi W, Harrelson J, Bateman KP. Zhang Q, et al. Among authors: hatcher ng. Anal Chem. 2014 Sep 2;86(17):8776-84. doi: 10.1021/ac5019827. Epub 2014 Aug 14. Anal Chem. 2014. PMID: 25010922

3

High-defined quantitative snapshots of the ganglioside lipidome using high resolution ion mobility SLIM assisted shotgun lipidomics.

Wormwood Moser KL, Van Aken G, DeBord D, Hatcher NG, Maxon L, Sherman M, Yao L, Ekroos K. Wormwood Moser KL, et al. Among authors: hatcher ng. Anal Chim Acta. 2021 Feb 15;1146:77-87. doi: 10.1016/j.aca.2020.12.022. Epub 2020 Dec 16. Anal Chim Acta. 2021. PMID: 33461722

4

Proteomic Discovery and Validation of Novel Fluid Biomarkers for Improved Patient Selection and Prediction of Clinical Outcomes in Alzheimer's Disease Patient Cohorts.

Awasthi S, Spellman DS, Hatcher NG. Awasthi S, et al. Among authors: hatcher ng. Proteomes. 2022 Aug 1;10(3):26. doi: 10.3390/proteomes10030026. Proteomes. 2022. PMID: 35997438 Free PMC article. Review.

5

A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy.

Cosden M, Jinn S, Yao L, Gretzula CA, Kandebo M, Toolan D, Hatcher NG, Ma L, Lemaire W, Adam GC, Burlein C, Minnick C, Flick R, Watt ML, Mulhearn J, Fraley M, Drolet RE, Marcus JN, Smith SM. Cosden M, et al. Among authors: hatcher ng. Neurobiol Dis. 2021 Nov;159:105507. doi: 10.1016/j.nbd.2021.105507. Epub 2021 Sep 9. Neurobiol Dis. 2021. PMID: 34509608 Free article.

6

LRRK2 inhibition prevents endolysosomal deficits seen in human Parkinson's disease.

Rocha EM, De Miranda BR, Castro S, Drolet R, Hatcher NG, Yao L, Smith SM, Keeney MT, Di Maio R, Kofler J, Hastings TG, Greenamyre JT. Rocha EM, et al. Among authors: hatcher ng. Neurobiol Dis. 2020 Feb;134:104626. doi: 10.1016/j.nbd.2019.104626. Epub 2019 Oct 13. Neurobiol Dis. 2020. PMID: 31618685 Free PMC article.

7

A sensitive aβ oligomer assay discriminates Alzheimer's and aged control cerebrospinal fluid.

Savage MJ, Kalinina J, Wolfe A, Tugusheva K, Korn R, Cash-Mason T, Maxwell JW, Hatcher NG, Haugabook SJ, Wu G, Howell BJ, Renger JJ, Shughrue PJ, McCampbell A. Savage MJ, et al. Among authors: hatcher ng. J Neurosci. 2014 Feb 19;34(8):2884-97. doi: 10.1523/JNEUROSCI.1675-13.2014. J Neurosci. 2014. PMID: 24553930 Free PMC article.

8

Internalized Tau Oligomers Cause Neurodegeneration by Inducing Accumulation of Pathogenic Tau in Human Neurons Derived from Induced Pluripotent Stem Cells.

Usenovic M, Niroomand S, Drolet RE, Yao L, Gaspar RC, Hatcher NG, Schachter J, Renger JJ, Parmentier-Batteur S. Usenovic M, et al. Among authors: hatcher ng. J Neurosci. 2015 Oct 21;35(42):14234-50. doi: 10.1523/JNEUROSCI.1523-15.2015. J Neurosci. 2015. PMID: 26490863 Free PMC article.

9

Using measures of metabolic flux to align screening and clinical development: Avoiding pitfalls to enable translational studies.

Satapati S, Downes DP, Metzger D, Shankaran H, Talukdar S, Zhou Y, Ren Z, Chen M, Lim YH, Hatcher NG, Wen X, Sheth PR, McLaren DG, Previs SF. Satapati S, et al. Among authors: hatcher ng. SLAS Discov. 2022 Jan;27(1):20-28. doi: 10.1016/j.slasd.2021.10.015. Epub 2021 Nov 2. SLAS Discov. 2022. PMID: 35058172 Free article.

10

Collecting peptide release from the brain using porous polymer monolith-based solid phase extraction capillaries.

Iannacone JM, Ren S, Hatcher NG, Sweedler JV. Iannacone JM, et al. Among authors: hatcher ng. Anal Chem. 2009 Jul 1;81(13):5433-8. doi: 10.1021/ac9005843. Anal Chem. 2009. PMID: 19485405 Free PMC article.

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