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Room-Temperature Cu(II) Radical-Triggered Alkyne C-H Activation.
Devonport J, Sully L, Boudalis AK, Hassell-Hart S, Leech MC, Lam K, Abdul-Sada A, Tizzard GJ, Coles SJ, Spencer J, Vargas A, Kostakis GE. Devonport J, et al. Among authors: hassell hart s. JACS Au. 2021 Oct 6;1(11):1937-1948. doi: 10.1021/jacsau.1c00310. eCollection 2021 Nov 22. JACS Au. 2021. PMID: 34841411 Free PMC article.
Chirality: a key parameter in chemical probes.
McGown A, Nafie J, Otayfah M, Hassell-Hart S, Tizzard GJ, Coles SJ, Banks R, Marsh GP, Maple HJ, Kostakis GE, Proietti Silvestri I, Colbon P, Spencer J. McGown A, et al. Among authors: hassell hart s. RSC Chem Biol. 2023 Aug 8;4(10):716-721. doi: 10.1039/d3cb00082f. eCollection 2023 Oct 4. RSC Chem Biol. 2023. PMID: 37799583 Free PMC article.
Deliberately Losing Control of C-H Activation Processes in the Design of Small-Molecule-Fragment Arrays Targeting Peroxisomal Metabolism.
Khan Tareque R, Hassell-Hart S, Krojer T, Bradley A, Velupillai S, Talon R, Fairhead M, Day IJ, Bala K, Felix R, Kemmitt PD, Brennan P, von Delft F, Díaz Sáez L, Huber K, Spencer J. Khan Tareque R, et al. ChemMedChem. 2020 Dec 15;15(24):2513-2520. doi: 10.1002/cmdc.202000543. Epub 2020 Sep 28. ChemMedChem. 2020. PMID: 32812371
Metallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain-like Protease PLpro.
Gil-Moles M, Türck S, Basu U, Pettenuzzo A, Bhattacharya S, Rajan A, Ma X, Büssing R, Wölker J, Burmeister H, Hoffmeister H, Schneeberg P, Prause A, Lippmann P, Kusi-Nimarko J, Hassell-Hart S, McGown A, Guest D, Lin Y, Notaro A, Vinck R, Karges J, Cariou K, Peng K, Qin X, Wang X, Skiba J, Szczupak Ł, Kowalski K, Schatzschneider U, Hemmert C, Gornitzka H, Milaeva ER, Nazarov AA, Gasser G, Spencer J, Ronconi L, Kortz U, Cinatl J, Bojkova D, Ott I. Gil-Moles M, et al. Among authors: hassell hart s. Chemistry. 2021 Dec 20;27(71):17928-17940. doi: 10.1002/chem.202103258. Epub 2021 Nov 23. Chemistry. 2021. PMID: 34714566 Free PMC article.
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