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Analysis of Structure-Activity Relationships of Novel Inhibitors of the Macrophage Infectivity Potentiator (Mip) Proteins of Neisseria meningitidis, Neisseria gonorrhoeae, and Burkholderia pseudomallei.
Scheuplein NJ, Bzdyl NM, Lohr T, Kibble EA, Hasenkopf A, Herbst C, Sarkar-Tyson M, Holzgrabe U. Scheuplein NJ, et al. Among authors: hasenkopf a. J Med Chem. 2023 Jul 13;66(13):8876-8895. doi: 10.1021/acs.jmedchem.3c00458. Epub 2023 Jun 30. J Med Chem. 2023. PMID: 37389560
Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major.
Iwasaki J, Lorimer DD, Vivoli-Vega M, Kibble EA, Peacock CS, Abendroth J, Mayclin SJ, Dranow DM, Pierce PG, Fox D, Lewis M, Bzdyl NM, Kristensen SS, Inglis TJJ, Kahler CM, Bond CS, Hasenkopf A, Seufert F, Schmitz J, Marshall LE, Scott AE, Norville IH, Myler PJ, Holzgrabe U, Harmer NJ, Sarkar-Tyson M. Iwasaki J, et al. Among authors: hasenkopf a. J Antimicrob Chemother. 2022 May 29;77(6):1625-1634. doi: 10.1093/jac/dkac065. J Antimicrob Chemother. 2022. PMID: 35245364 Free PMC article.