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Structure of the peripheral arm of a minimalistic respiratory complex I.
Schimpf J, Oppermann S, Gerasimova T, Santos Seica AF, Hellwig P, Grishkovskaya I, Wohlwend D, Haselbach D, Friedrich T. Schimpf J, et al. Among authors: haselbach d. Structure. 2022 Jan 6;30(1):80-94.e4. doi: 10.1016/j.str.2021.09.005. Epub 2021 Sep 24. Structure. 2022. PMID: 34562374 Free article.
Quantifying the heterogeneity of macromolecular machines by mass photometry.
Sonn-Segev A, Belacic K, Bodrug T, Young G, VanderLinden RT, Schulman BA, Schimpf J, Friedrich T, Dip PV, Schwartz TU, Bauer B, Peters JM, Struwe WB, Benesch JLP, Brown NG, Haselbach D, Kukura P. Sonn-Segev A, et al. Among authors: haselbach d. Nat Commun. 2020 Apr 14;11(1):1772. doi: 10.1038/s41467-020-15642-w. Nat Commun. 2020. PMID: 32286308 Free PMC article.
Structural basis for inhibition of the AAA-ATPase Drg1 by diazaborine.
Prattes M, Grishkovskaya I, Hodirnau VV, Rössler I, Klein I, Hetzmannseder C, Zisser G, Gruber CC, Gruber K, Haselbach D, Bergler H. Prattes M, et al. Among authors: haselbach d. Nat Commun. 2021 Jun 9;12(1):3483. doi: 10.1038/s41467-021-23854-x. Nat Commun. 2021. PMID: 34108481 Free PMC article.
The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains.
Rodriguez Carvajal A, Grishkovskaya I, Gomez Diaz C, Vogel A, Sonn-Segev A, Kushwah MS, Schodl K, Deszcz L, Orban-Nemeth Z, Sakamoto S, Mechtler K, Kukura P, Clausen T, Haselbach D, Ikeda F. Rodriguez Carvajal A, et al. Among authors: haselbach d. Elife. 2021 Jun 18;10:e60660. doi: 10.7554/eLife.60660. Elife. 2021. PMID: 34142657 Free PMC article.
HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain.
Grabarczyk DB, Petrova OA, Deszcz L, Kurzbauer R, Murphy P, Ahel J, Vogel A, Gogova R, Faas V, Kordic D, Schleiffer A, Meinhart A, Imre R, Lehner A, Neuhold J, Bader G, Stolt-Bergner P, Böttcher J, Wolkerstorfer B, Fischer G, Grishkovskaya I, Haselbach D, Kessler D, Clausen T. Grabarczyk DB, et al. Among authors: haselbach d. Nat Chem Biol. 2021 Oct;17(10):1084-1092. doi: 10.1038/s41589-021-00831-5. Epub 2021 Jul 22. Nat Chem Biol. 2021. PMID: 34294896 Free PMC article.
AKIRIN2 controls the nuclear import of proteasomes in vertebrates.
de Almeida M, Hinterndorfer M, Brunner H, Grishkovskaya I, Singh K, Schleiffer A, Jude J, Deswal S, Kalis R, Vunjak M, Lendl T, Imre R, Roitinger E, Neumann T, Kandolf S, Schutzbier M, Mechtler K, Versteeg GA, Haselbach D, Zuber J. de Almeida M, et al. Among authors: haselbach d. Nature. 2021 Nov;599(7885):491-496. doi: 10.1038/s41586-021-04035-8. Epub 2021 Oct 28. Nature. 2021. PMID: 34711951
Cryo-EM structure of the plant 26S proteasome.
Kandolf S, Grishkovskaya I, Belačić K, Bolhuis DL, Amann S, Foster B, Imre R, Mechtler K, Schleiffer A, Tagare HD, Zhong ED, Meinhart A, Brown NG, Haselbach D. Kandolf S, et al. Among authors: haselbach d. Plant Commun. 2022 May 9;3(3):100310. doi: 10.1016/j.xplc.2022.100310. Epub 2022 Mar 11. Plant Commun. 2022. PMID: 35576154 Free PMC article.
Visualizing maturation factor extraction from the nascent ribosome by the AAA-ATPase Drg1.
Prattes M, Grishkovskaya I, Hodirnau VV, Hetzmannseder C, Zisser G, Sailer C, Kargas V, Loibl M, Gerhalter M, Kofler L, Warren AJ, Stengel F, Haselbach D, Bergler H. Prattes M, et al. Among authors: haselbach d. Nat Struct Mol Biol. 2022 Sep;29(9):942-953. doi: 10.1038/s41594-022-00832-5. Epub 2022 Sep 12. Nat Struct Mol Biol. 2022. PMID: 36097293 Free PMC article.
36 results