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TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Arseni D, Chen R, Murzin AG, Peak-Chew SY, Garringer HJ, Newell KL, Kametani F, Robinson AC, Vidal R, Ghetti B, Hasegawa M, Ryskeldi-Falcon B. Arseni D, et al. Among authors: hasegawa m. Nature. 2023 Aug;620(7975):898-903. doi: 10.1038/s41586-023-06405-w. Epub 2023 Aug 2. Nature. 2023. PMID: 37532939 Free PMC article.
[Frontotemporal dementia (FTD) and genetic mutations including progranulin gene].
Arai T, Hasegawa M, Nishihara M, Nonaka T, Kametani F, Yoshida M, Hashizume Y, Beach TG, Morita M, Nakano I, Oda T, Tsuchiya K, Akiyama H. Arai T, et al. Among authors: hasegawa m. Rinsho Shinkeigaku. 2008 Nov;48(11):990-3. doi: 10.5692/clinicalneurol.48.990. Rinsho Shinkeigaku. 2008. PMID: 19198141 Review. Japanese.
[Significance of the TDP-43 deposition in FTLD-U and ALS].
Hasegawa M, Arai T, Nonaka T, Kametani F, Yoshida M, Hashizume Y, Beach TG, Morita M, Nakano I, Oda T, Tsuchiya K, Akiyama H. Hasegawa M, et al. Rinsho Shinkeigaku. 2008 Nov;48(11):994-7. doi: 10.5692/clinicalneurol.48.994. Rinsho Shinkeigaku. 2008. PMID: 19198142 Review. Japanese.
Identification of casein kinase-1 phosphorylation sites on TDP-43.
Kametani F, Nonaka T, Suzuki T, Arai T, Dohmae N, Akiyama H, Hasegawa M. Kametani F, et al. Among authors: hasegawa m. Biochem Biophys Res Commun. 2009 May 1;382(2):405-9. doi: 10.1016/j.bbrc.2009.03.038. Epub 2009 Mar 13. Biochem Biophys Res Commun. 2009. PMID: 19285963
Methylene blue and dimebon inhibit aggregation of TDP-43 in cellular models.
Yamashita M, Nonaka T, Arai T, Kametani F, Buchman VL, Ninkina N, Bachurin SO, Akiyama H, Goedert M, Hasegawa M. Yamashita M, et al. Among authors: hasegawa m. FEBS Lett. 2009 Jul 21;583(14):2419-24. doi: 10.1016/j.febslet.2009.06.042. Epub 2009 Jun 26. FEBS Lett. 2009. PMID: 19560462 Free article.
Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy.
Arai T, Hasegawa M, Nonoka T, Kametani F, Yamashita M, Hosokawa M, Niizato K, Tsuchiya K, Kobayashi Z, Ikeda K, Yoshida M, Onaya M, Fujishiro H, Akiyama H. Arai T, et al. Among authors: hasegawa m. Neuropathology. 2010 Apr;30(2):170-81. doi: 10.1111/j.1440-1789.2009.01089.x. Epub 2010 Jan 19. Neuropathology. 2010. PMID: 20102522 Review.
Molecular dissection of TDP-43 proteinopathies.
Hasegawa M, Nonaka T, Tsuji H, Tamaoka A, Yamashita M, Kametani F, Yoshida M, Arai T, Akiyama H. Hasegawa M, et al. J Mol Neurosci. 2011 Nov;45(3):480-5. doi: 10.1007/s12031-011-9571-x. Epub 2011 Jun 16. J Mol Neurosci. 2011. PMID: 21678031
4,134 results