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KUS121, a VCP modulator, has an ameliorating effect on acute and chronic heart failure without calcium loading via maintenance of intracellular ATP levels.
Tsuji S, Otani C, Horie T, Watanabe S, Baba O, Sowa N, Ide Y, Kashiwa A, Makiyama T, Imai H, Nakashima Y, Yamasaki T, Xu S, Matsushita K, Suzuki K, Zou F, Kume E, Hasegawa K, Kimura T, Kakizuka A, Ono K. Tsuji S, et al. Among authors: hasegawa k. Biomed Pharmacother. 2024 Jan;170:115850. doi: 10.1016/j.biopha.2023.115850. Epub 2023 Dec 12. Biomed Pharmacother. 2024. PMID: 38091636 Free article.
6-Shogaol, an Active Component of Ginger, Inhibits p300 Histone Acetyltransferase Activity and Attenuates the Development of Pressure-Overload-Induced Heart Failure.
Kawase Y, Sunagawa Y, Shimizu K, Funamoto M, Hamabe-Horiike T, Katanasaka Y, Shimizu S, Hawke P, Mori K, Komiyama M, Hasegawa K, Morimoto T. Kawase Y, et al. Among authors: hasegawa k. Nutrients. 2023 May 8;15(9):2232. doi: 10.3390/nu15092232. Nutrients. 2023. PMID: 37432400 Free PMC article.
Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice.
Katanasaka Y, Yabe H, Murata N, Sobukawa M, Sugiyama Y, Sato H, Honda H, Sunagawa Y, Funamoto M, Shimizu S, Shimizu K, Hamabe-Horiike T, Hawke P, Komiyama M, Mori K, Hasegawa K, Morimoto T. Katanasaka Y, et al. Among authors: hasegawa k. Nat Commun. 2024 Mar 19;15(1):2472. doi: 10.1038/s41467-024-46711-z. Nat Commun. 2024. PMID: 38503742 Free PMC article.
Anserine, a Histidine-Containing Dipeptide, Suppresses Pressure Overload-Induced Systolic Dysfunction by Inhibiting Histone Acetyltransferase Activity of p300 in Mice.
Sunagawa Y, Tsukabe R, Irokawa Y, Funamoto M, Suzuki Y, Yamada M, Shimizu S, Katanasaka Y, Hamabe-Horiike T, Kawase Y, Naruta R, Shimizu K, Mori K, Hosomi R, Komiyama M, Hasegawa K, Morimoto T. Sunagawa Y, et al. Among authors: hasegawa k. Int J Mol Sci. 2024 Feb 16;25(4):2344. doi: 10.3390/ijms25042344. Int J Mol Sci. 2024. PMID: 38397020 Free PMC article.
Randomised Double-blind Placebo-Controlled Multicentre Trial for the Effects of Yokukansan in Smokers with Depressive Tendencies.
Komiyama M, Ozaki Y, Wada H, Yamakage H, Satoh-Asahara N, Yasoda A, Sunagawa Y, Morimoto T, Takahashi Y, Hasegawa K. Komiyama M, et al. Among authors: hasegawa k. Eur Cardiol. 2023 Apr 25;18:e30. doi: 10.15420/ecr.2023.18.PO13. eCollection 2023. Eur Cardiol. 2023. PMID: 37405335 Free PMC article. Review. No abstract available.
4,335 results