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Chromosome errors in human eggs shape natural fertility over reproductive life span.
Gruhn JR, Zielinska AP, Shukla V, Blanshard R, Capalbo A, Cimadomo D, Nikiforov D, Chan AC, Newnham LJ, Vogel I, Scarica C, Krapchev M, Taylor D, Kristensen SG, Cheng J, Ernst E, Bjørn AB, Colmorn LB, Blayney M, Elder K, Liss J, Hartshorne G, Grøndahl ML, Rienzi L, Ubaldi F, McCoy R, Lukaszuk K, Andersen CY, Schuh M, Hoffmann ER. Gruhn JR, et al. Among authors: hartshorne g. Science. 2019 Sep 27;365(6460):1466-1469. doi: 10.1126/science.aav7321. Science. 2019. PMID: 31604276 Free PMC article.
The first mitotic division of human embryos is highly error prone.
Currie CE, Ford E, Benham Whyte L, Taylor DM, Mihalas BP, Erent M, Marston AL, Hartshorne GM, McAinsh AD. Currie CE, et al. Among authors: hartshorne gm. Nat Commun. 2022 Nov 8;13(1):6755. doi: 10.1038/s41467-022-34294-6. Nat Commun. 2022. PMID: 36347869 Free PMC article.
68 results